{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 2519
    },
    {
      "term": "Anorexia",
      "count": 1326
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 1078
    },
    {
      "term": "Diarrhoea",
      "count": 932
    },
    {
      "term": "Elevated creatinine",
      "count": 807
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 791
    },
    {
      "term": "Death",
      "count": 786
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 715
    },
    {
      "term": "Depression",
      "count": 699
    },
    {
      "term": "Death by euthanasia",
      "count": 692
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 547
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 424
    },
    {
      "term": "Anaemia NOS",
      "count": 402
    },
    {
      "term": "Ataxia",
      "count": 374
    },
    {
      "term": "Polydipsia",
      "count": 342
    },
    {
      "term": "Leucocytosis NOS",
      "count": 338
    },
    {
      "term": "Hyperphosphataemia",
      "count": 324
    },
    {
      "term": "Intestinal perforation",
      "count": 315
    },
    {
      "term": "Bloody diarrhoea",
      "count": 313
    },
    {
      "term": "Melaena",
      "count": 282
    },
    {
      "term": "Weight loss",
      "count": 274
    },
    {
      "term": "INEFFECTIVE, ANALGESIA",
      "count": 272
    },
    {
      "term": "Peritonitis",
      "count": 255
    },
    {
      "term": "Elevated total bilirubin",
      "count": 251
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 246
    },
    {
      "term": "Labelled drug-drug interaction medication error",
      "count": 244
    },
    {
      "term": "Blood in vomit",
      "count": 233
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 233
    },
    {
      "term": "Abdominal pain",
      "count": 230
    },
    {
      "term": "INEFFECTIVE, ANTIINFLAMMATORY",
      "count": 220
    },
    {
      "term": "Not eating",
      "count": 216
    },
    {
      "term": "Convulsion",
      "count": 212
    },
    {
      "term": "Neutrophilia",
      "count": 206
    },
    {
      "term": "Thrombocytopenia",
      "count": 206
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 194
    },
    {
      "term": "Polyuria",
      "count": 176
    },
    {
      "term": "Decreased urine concentration",
      "count": 175
    },
    {
      "term": "Elevated liver enzymes",
      "count": 173
    },
    {
      "term": "Small intestine ulcer",
      "count": 169
    },
    {
      "term": "Weakness",
      "count": 160
    },
    {
      "term": "Elevated amylase",
      "count": 159
    },
    {
      "term": "Seizure NOS",
      "count": 157
    },
    {
      "term": "Hypoproteinaemia",
      "count": 155
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 151
    },
    {
      "term": "Haematuria",
      "count": 149
    },
    {
      "term": "Pale mucous membrane",
      "count": 148
    },
    {
      "term": "Dehydration",
      "count": 144
    },
    {
      "term": "Recumbency",
      "count": 143
    },
    {
      "term": "Renal failure",
      "count": 142
    },
    {
      "term": "Inappetence",
      "count": 141
    },
    {
      "term": "Pain NOS",
      "count": 134
    },
    {
      "term": "Pruritus",
      "count": 134
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 133
    },
    {
      "term": "Hyperkalaemia",
      "count": 132
    },
    {
      "term": "Overdose",
      "count": 128
    },
    {
      "term": "Gastric perforation",
      "count": 127
    },
    {
      "term": "Decreased appetite",
      "count": 126
    },
    {
      "term": "Accidental exposure",
      "count": 125
    },
    {
      "term": "Icterus",
      "count": 125
    },
    {
      "term": "Panting",
      "count": 125
    },
    {
      "term": "Ascites",
      "count": 121
    },
    {
      "term": "Adipsia",
      "count": 119
    },
    {
      "term": "Restlessness",
      "count": 119
    },
    {
      "term": "Hyperglycaemia",
      "count": 118
    },
    {
      "term": "Emesis",
      "count": 115
    },
    {
      "term": "Polypnoea",
      "count": 114
    },
    {
      "term": "Reluctant to move",
      "count": 110
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 109
    },
    {
      "term": "Dyspnoea",
      "count": 109
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 106
    },
    {
      "term": "Loose stool",
      "count": 104
    },
    {
      "term": "Proteinuria",
      "count": 101
    },
    {
      "term": "Tachycardia",
      "count": 101
    },
    {
      "term": "Fever",
      "count": 100
    },
    {
      "term": "Vocalisation",
      "count": 100
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 91
    },
    {
      "term": "Gastric ulcer",
      "count": 91
    },
    {
      "term": "Urinary incontinence",
      "count": 90
    },
    {
      "term": "Epistaxis",
      "count": 87
    },
    {
      "term": "Elevated lipase",
      "count": 86
    },
    {
      "term": "Leucopenia NOS",
      "count": 86
    },
    {
      "term": "Hind limb paresis",
      "count": 85
    },
    {
      "term": "Distension of abdomen",
      "count": 83
    },
    {
      "term": "Confusion",
      "count": 82
    },
    {
      "term": "Haematochezia",
      "count": 82
    },
    {
      "term": "Hypersalivation",
      "count": 82
    },
    {
      "term": "Monocytosis",
      "count": 79
    },
    {
      "term": "Trembling",
      "count": 79
    },
    {
      "term": "Elevated renal parameters",
      "count": 76
    },
    {
      "term": "Hyperactivity",
      "count": 76
    },
    {
      "term": "Tarry or black stool (see also haemorrhagic diarrhoea)",
      "count": 75
    },
    {
      "term": "Lymphopenia",
      "count": 74
    },
    {
      "term": "Elevated globulins",
      "count": 72
    },
    {
      "term": "Oedema of the extremities (see also other SOCs for most applicable oedema)",
      "count": 72
    },
    {
      "term": "Duodenal ulcer",
      "count": 71
    },
    {
      "term": "Aggression",
      "count": 70
    },
    {
      "term": "Hyperproteinaemia",
      "count": 70
    },
    {
      "term": "Pancreatitis",
      "count": 70
    },
    {
      "term": "Shaking",
      "count": 68
    },
    {
      "term": "PR-LIVER, LESION(S)",
      "count": 67
    }
  ]
}