{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 1115
    },
    {
      "term": "Diarrhoea",
      "count": 583
    },
    {
      "term": "Depression",
      "count": 497
    },
    {
      "term": "Anorexia",
      "count": 493
    },
    {
      "term": "Lack of efficacy (endoparasite) - hookworm",
      "count": 309
    },
    {
      "term": "Death",
      "count": 236
    },
    {
      "term": "Lack of efficacy (endoparasite) - tapeworm",
      "count": 139
    },
    {
      "term": "INEFFECTIVE, HOOKS",
      "count": 132
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 128
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 116
    },
    {
      "term": "Bloody diarrhoea",
      "count": 102
    },
    {
      "term": "Death by euthanasia",
      "count": 94
    },
    {
      "term": "Vocalisation",
      "count": 89
    },
    {
      "term": "Ataxia",
      "count": 86
    },
    {
      "term": "Hyperactivity",
      "count": 86
    },
    {
      "term": "Emesis",
      "count": 82
    },
    {
      "term": "Adipsia",
      "count": 79
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 77
    },
    {
      "term": "Weakness",
      "count": 75
    },
    {
      "term": "Lack of efficacy (endoparasite) - roundworm NOS",
      "count": 74
    },
    {
      "term": "Loose stool",
      "count": 72
    },
    {
      "term": "Lack of efficacy (endoparasite) - NOS",
      "count": 70
    },
    {
      "term": "Trembling",
      "count": 68
    },
    {
      "term": "Fever",
      "count": 67
    },
    {
      "term": "Weight loss",
      "count": 67
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 62
    },
    {
      "term": "Dehydration",
      "count": 61
    },
    {
      "term": "Lack of efficacy (endoparasite) - whipworm",
      "count": 59
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 58
    },
    {
      "term": "Cough",
      "count": 56
    },
    {
      "term": "Retching",
      "count": 56
    },
    {
      "term": "Restlessness",
      "count": 52
    },
    {
      "term": "Lack of efficacy (endoparasite) - heartworm",
      "count": 51
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 51
    },
    {
      "term": "Hypersalivation",
      "count": 49
    },
    {
      "term": "Not eating",
      "count": 49
    },
    {
      "term": "Convulsion",
      "count": 48
    },
    {
      "term": "Emesis (multiple)",
      "count": 48
    },
    {
      "term": "Seizure NOS",
      "count": 47
    },
    {
      "term": "Underdose",
      "count": 46
    },
    {
      "term": "Anaemia NOS",
      "count": 45
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 43
    },
    {
      "term": "Haematochezia",
      "count": 43
    },
    {
      "term": "Shaking",
      "count": 42
    },
    {
      "term": "Overdose",
      "count": 40
    },
    {
      "term": "Polydipsia",
      "count": 40
    },
    {
      "term": "Accidental exposure",
      "count": 39
    },
    {
      "term": "Leucocytosis NOS",
      "count": 38
    },
    {
      "term": "INEFFECTIVE, ASCARIDS NOS",
      "count": 37
    },
    {
      "term": "Pruritus",
      "count": 37
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 36
    },
    {
      "term": "Pain NOS",
      "count": 36
    },
    {
      "term": "Polyuria",
      "count": 34
    },
    {
      "term": "Pale mucous membrane",
      "count": 32
    },
    {
      "term": "Neutrophilia",
      "count": 31
    },
    {
      "term": "Facial oedema",
      "count": 30
    },
    {
      "term": "Decreased appetite",
      "count": 28
    },
    {
      "term": "Mucous stool",
      "count": 28
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 26
    },
    {
      "term": "Recumbency",
      "count": 26
    },
    {
      "term": "Urticaria",
      "count": 26
    },
    {
      "term": "Abdominal pain",
      "count": 25
    },
    {
      "term": "Anaphylaxis",
      "count": 25
    },
    {
      "term": "Malaise",
      "count": 25
    },
    {
      "term": "Leucopenia NOS",
      "count": 24
    },
    {
      "term": "Polypnoea",
      "count": 24
    },
    {
      "term": "Blood in vomit",
      "count": 23
    },
    {
      "term": "Constipation",
      "count": 23
    },
    {
      "term": "Hypoglycaemia",
      "count": 23
    },
    {
      "term": "Dyspnoea",
      "count": 22
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 22
    },
    {
      "term": "Lack of efficacy (protozoa) - Giardia",
      "count": 22
    },
    {
      "term": "Drug dose administration interval too short",
      "count": 21
    },
    {
      "term": "Hypothermia",
      "count": 21
    },
    {
      "term": "Distension of abdomen",
      "count": 20
    },
    {
      "term": "INEFFECTIVE, WORMS NOS",
      "count": 20
    },
    {
      "term": "Inappetence",
      "count": 20
    },
    {
      "term": "Lack of efficacy (protozoa) - Coccidia",
      "count": 20
    },
    {
      "term": "Tachycardia",
      "count": 20
    },
    {
      "term": "Lameness",
      "count": 19
    },
    {
      "term": "Reluctant to move",
      "count": 19
    },
    {
      "term": "Thrombocytopenia",
      "count": 19
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 18
    },
    {
      "term": "Elevated liver enzymes",
      "count": 18
    },
    {
      "term": "Haematuria",
      "count": 18
    },
    {
      "term": "Icterus",
      "count": 18
    },
    {
      "term": "Anxiety",
      "count": 17
    },
    {
      "term": "Drooling",
      "count": 17
    },
    {
      "term": "Elevated total bilirubin",
      "count": 17
    },
    {
      "term": "Hypoproteinaemia",
      "count": 17
    },
    {
      "term": "Lack of efficacy (virus) - parvovirus (including feline panleukopenia)",
      "count": 17
    },
    {
      "term": "Weight gain",
      "count": 17
    },
    {
      "term": "Flatulence",
      "count": 16
    },
    {
      "term": "Monocytosis",
      "count": 16
    },
    {
      "term": "Panting",
      "count": 16
    },
    {
      "term": "Skin lesion NOS",
      "count": 16
    },
    {
      "term": "Urinary incontinence",
      "count": 16
    },
    {
      "term": "Administration error NOS",
      "count": 15
    },
    {
      "term": "Hyperphosphataemia",
      "count": 15
    },
    {
      "term": "INEFFECTIVE, WHIPS",
      "count": 15
    }
  ]
}