{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 966
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 616
    },
    {
      "term": "Diarrhoea",
      "count": 412
    },
    {
      "term": "Anaphylaxis",
      "count": 365
    },
    {
      "term": "Death",
      "count": 337
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 308
    },
    {
      "term": "Death by euthanasia",
      "count": 302
    },
    {
      "term": "Anorexia",
      "count": 301
    },
    {
      "term": "Pale mucous membrane",
      "count": 278
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 275
    },
    {
      "term": "Leucocytosis NOS",
      "count": 243
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 242
    },
    {
      "term": "Fever",
      "count": 240
    },
    {
      "term": "Not eating",
      "count": 239
    },
    {
      "term": "Panting",
      "count": 225
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 209
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 204
    },
    {
      "term": "Seizure NOS",
      "count": 203
    },
    {
      "term": "Anaemia NOS",
      "count": 197
    },
    {
      "term": "Neutrophilia",
      "count": 191
    },
    {
      "term": "Emesis",
      "count": 187
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 177
    },
    {
      "term": "Weight loss",
      "count": 175
    },
    {
      "term": "Decreased appetite",
      "count": 174
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 174
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 168
    },
    {
      "term": "Ataxia",
      "count": 163
    },
    {
      "term": "Thrombocytopenia",
      "count": 160
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 145
    },
    {
      "term": "Bloody diarrhoea",
      "count": 144
    },
    {
      "term": "Weakness",
      "count": 144
    },
    {
      "term": "Elevated total bilirubin",
      "count": 138
    },
    {
      "term": "Tachycardia",
      "count": 131
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 127
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 125
    },
    {
      "term": "Vocalisation",
      "count": 123
    },
    {
      "term": "Dehydration",
      "count": 119
    },
    {
      "term": "Shaking",
      "count": 119
    },
    {
      "term": "Pruritus",
      "count": 118
    },
    {
      "term": "Polyuria",
      "count": 116
    },
    {
      "term": "Pain NOS",
      "count": 113
    },
    {
      "term": "Polydipsia",
      "count": 112
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 110
    },
    {
      "term": "Emesis (multiple)",
      "count": 109
    },
    {
      "term": "Lateral recumbency",
      "count": 108
    },
    {
      "term": "Deafness",
      "count": 104
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 102
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 100
    },
    {
      "term": "Hyperglycaemia",
      "count": 97
    },
    {
      "term": "Monocytosis",
      "count": 97
    },
    {
      "term": "Elevated liver enzymes",
      "count": 94
    },
    {
      "term": "Drooling",
      "count": 89
    },
    {
      "term": "Elevated creatinine",
      "count": 88
    },
    {
      "term": "Inappetence",
      "count": 86
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 85
    },
    {
      "term": "Hyperphosphataemia",
      "count": 84
    },
    {
      "term": "Facial swelling (see also Skin)",
      "count": 82
    },
    {
      "term": "Dyspnoea",
      "count": 81
    },
    {
      "term": "Low platelet count",
      "count": 80
    },
    {
      "term": "Tachypnoea",
      "count": 79
    },
    {
      "term": "Cough",
      "count": 78
    },
    {
      "term": "Hypotension",
      "count": 78
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 77
    },
    {
      "term": "Immune mediated haemolytic anaemia",
      "count": 77
    },
    {
      "term": "Hypothermia",
      "count": 76
    },
    {
      "term": "Pinnal erythema",
      "count": 76
    },
    {
      "term": "Loose stool",
      "count": 75
    },
    {
      "term": "Hypokalaemia",
      "count": 74
    },
    {
      "term": "Hypersalivation",
      "count": 73
    },
    {
      "term": "Lack of efficacy (endoparasite) - heartworm",
      "count": 73
    },
    {
      "term": "Urticaria",
      "count": 72
    },
    {
      "term": "Depression",
      "count": 70
    },
    {
      "term": "Reddening of the skin",
      "count": 69
    },
    {
      "term": "Leucopenia NOS",
      "count": 68
    },
    {
      "term": "Bruising",
      "count": 67
    },
    {
      "term": "Restlessness",
      "count": 67
    },
    {
      "term": "Inappropriate urination",
      "count": 64
    },
    {
      "term": "Lymphopenia",
      "count": 64
    },
    {
      "term": "Anxiety",
      "count": 63
    },
    {
      "term": "Cardiac arrest",
      "count": 63
    },
    {
      "term": "Decreased red blood cell count",
      "count": 63
    },
    {
      "term": "Unable to stand",
      "count": 63
    },
    {
      "term": "Hyponatremia",
      "count": 61
    },
    {
      "term": "Hypoproteinaemia",
      "count": 61
    },
    {
      "term": "Cyanosis",
      "count": 59
    },
    {
      "term": "Icterus",
      "count": 59
    },
    {
      "term": "Hives (see also Skin)",
      "count": 58
    },
    {
      "term": "Walking difficulty",
      "count": 58
    },
    {
      "term": "Breathing difficulty",
      "count": 57
    },
    {
      "term": "Injection site swelling",
      "count": 57
    },
    {
      "term": "Respiratory distress",
      "count": 57
    },
    {
      "term": "Bradycardia",
      "count": 56
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 56
    },
    {
      "term": "Elevated temperature",
      "count": 56
    },
    {
      "term": "Not drinking",
      "count": 56
    },
    {
      "term": "Corneal ulcer",
      "count": 55
    },
    {
      "term": "Haematuria",
      "count": 55
    },
    {
      "term": "Laboured breathing",
      "count": 55
    },
    {
      "term": "Urinary incontinence",
      "count": 54
    },
    {
      "term": "Blood in vomit",
      "count": 52
    }
  ]
}