{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "High sodium-potassium ratio (Na:K ratio)",
      "count": 199
    },
    {
      "term": "Vomiting",
      "count": 171
    },
    {
      "term": "Polyuria",
      "count": 166
    },
    {
      "term": "Polydipsia",
      "count": 160
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 135
    },
    {
      "term": "Weight gain",
      "count": 122
    },
    {
      "term": "Diarrhoea",
      "count": 106
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 102
    },
    {
      "term": "Weight loss",
      "count": 94
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 92
    },
    {
      "term": "Hypokalaemia",
      "count": 87
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 72
    },
    {
      "term": "Not eating",
      "count": 69
    },
    {
      "term": "Underdose",
      "count": 65
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 60
    },
    {
      "term": "Decreased appetite",
      "count": 58
    },
    {
      "term": "Incorrect route of drug administration",
      "count": 56
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 55
    },
    {
      "term": "Hyperkalaemia",
      "count": 54
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 53
    },
    {
      "term": "Hyponatremia",
      "count": 53
    },
    {
      "term": "Immediate pain upon injection",
      "count": 51
    },
    {
      "term": "Malaise",
      "count": 49
    },
    {
      "term": "Hypochloraemia",
      "count": 48
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 46
    },
    {
      "term": "Death by euthanasia",
      "count": 43
    },
    {
      "term": "Inappropriate urination",
      "count": 43
    },
    {
      "term": "Urinary tract infection",
      "count": 43
    },
    {
      "term": "Elevated creatinine",
      "count": 41
    },
    {
      "term": "Death",
      "count": 40
    },
    {
      "term": "Shaking",
      "count": 40
    },
    {
      "term": "Urinary incontinence",
      "count": 39
    },
    {
      "term": "Hypernatremia",
      "count": 38
    },
    {
      "term": "Decreased urine concentration",
      "count": 35
    },
    {
      "term": "Leucocytosis NOS",
      "count": 34
    },
    {
      "term": "Electrolyte disorder",
      "count": 33
    },
    {
      "term": "INEFFECTIVE, OTHER DRUG(S)",
      "count": 33
    },
    {
      "term": "Panting",
      "count": 33
    },
    {
      "term": "Anorexia",
      "count": 32
    },
    {
      "term": "Anaemia NOS",
      "count": 31
    },
    {
      "term": "Dehydration",
      "count": 31
    },
    {
      "term": "Anxiety",
      "count": 29
    },
    {
      "term": "Hyperphosphataemia",
      "count": 29
    },
    {
      "term": "Injection site pain",
      "count": 29
    },
    {
      "term": "Neutrophilia",
      "count": 28
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 27
    },
    {
      "term": "Weakness",
      "count": 27
    },
    {
      "term": "Low sodium-potassium ratio (Na:K ratio)",
      "count": 26
    },
    {
      "term": "Arthritis",
      "count": 25
    },
    {
      "term": "Vocalisation",
      "count": 24
    },
    {
      "term": "Seizure NOS",
      "count": 23
    },
    {
      "term": "Hyperglycaemia",
      "count": 21
    },
    {
      "term": "Polyphagia",
      "count": 21
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 19
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 19
    },
    {
      "term": "Unwell",
      "count": 19
    },
    {
      "term": "Elevated liver enzymes",
      "count": 18
    },
    {
      "term": "Hypoglycaemia",
      "count": 18
    },
    {
      "term": "Loose stool",
      "count": 18
    },
    {
      "term": "Anaphylaxis",
      "count": 17
    },
    {
      "term": "Decreased red blood cell count",
      "count": 17
    },
    {
      "term": "Fever",
      "count": 17
    },
    {
      "term": "Hair loss NOS",
      "count": 17
    },
    {
      "term": "Inappetence",
      "count": 17
    },
    {
      "term": "Thrombocytopenia",
      "count": 17
    },
    {
      "term": "Medication error",
      "count": 16
    },
    {
      "term": "Not himself/herself",
      "count": 16
    },
    {
      "term": "Proteinuria",
      "count": 16
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 15
    },
    {
      "term": "Allergic reaction",
      "count": 15
    },
    {
      "term": "Azotaemia",
      "count": 15
    },
    {
      "term": "Decreased haematocrit",
      "count": 15
    },
    {
      "term": "Depression",
      "count": 15
    },
    {
      "term": "Emesis (multiple)",
      "count": 15
    },
    {
      "term": "Heart murmur",
      "count": 15
    },
    {
      "term": "Restlessness",
      "count": 15
    },
    {
      "term": "Systemic disorder NOS",
      "count": 15
    },
    {
      "term": "Bloody diarrhoea",
      "count": 14
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 14
    },
    {
      "term": "Elevated amylase",
      "count": 14
    },
    {
      "term": "Haemolysis NOS",
      "count": 14
    },
    {
      "term": "Hair change",
      "count": 14
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 14
    },
    {
      "term": "Overdose",
      "count": 14
    },
    {
      "term": "Trembling",
      "count": 14
    },
    {
      "term": "Defect Unknown/Not Specified",
      "count": 13
    },
    {
      "term": "Facial swelling (see also Skin)",
      "count": 13
    },
    {
      "term": "Hypercalcaemia",
      "count": 13
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 13
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 12
    },
    {
      "term": "Aggression",
      "count": 12
    },
    {
      "term": "Cough",
      "count": 12
    },
    {
      "term": "Drug dose administration interval too long",
      "count": 12
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 12
    },
    {
      "term": "Hypocortisolaemia",
      "count": 12
    },
    {
      "term": "Itching",
      "count": 12
    },
    {
      "term": "Limb weakness",
      "count": 12
    },
    {
      "term": "Not drinking",
      "count": 12
    },
    {
      "term": "Product Defect, General",
      "count": 12
    },
    {
      "term": "Bradycardia",
      "count": 11
    }
  ]
}