{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 4514
    },
    {
      "term": "Diarrhoea",
      "count": 2556
    },
    {
      "term": "Depression",
      "count": 1288
    },
    {
      "term": "Anorexia",
      "count": 1211
    },
    {
      "term": "Pruritus",
      "count": 1120
    },
    {
      "term": "Emesis",
      "count": 875
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 717
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 712
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 691
    },
    {
      "term": "INEFFECTIVE, ATOPY CONTROL",
      "count": 604
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 585
    },
    {
      "term": "Gingival hyperplasia",
      "count": 564
    },
    {
      "term": "Weight loss",
      "count": 500
    },
    {
      "term": "Death by euthanasia",
      "count": 480
    },
    {
      "term": "Polydipsia",
      "count": 461
    },
    {
      "term": "Polyuria",
      "count": 419
    },
    {
      "term": "Trembling",
      "count": 383
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 344
    },
    {
      "term": "Loose stool",
      "count": 340
    },
    {
      "term": "Polypnoea",
      "count": 325
    },
    {
      "term": "Labelled drug-drug interaction medication error",
      "count": 324
    },
    {
      "term": "Restlessness",
      "count": 323
    },
    {
      "term": "Hyperactivity",
      "count": 307
    },
    {
      "term": "Convulsion",
      "count": 296
    },
    {
      "term": "Emesis (multiple)",
      "count": 290
    },
    {
      "term": "Bloody diarrhoea",
      "count": 271
    },
    {
      "term": "Leucocytosis NOS",
      "count": 271
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 269
    },
    {
      "term": "Anaemia NOS",
      "count": 261
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 258
    },
    {
      "term": "Dermal mass",
      "count": 254
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 253
    },
    {
      "term": "Ataxia",
      "count": 243
    },
    {
      "term": "Panting",
      "count": 240
    },
    {
      "term": "Death",
      "count": 232
    },
    {
      "term": "Skin lesion NOS",
      "count": 232
    },
    {
      "term": "Decreased appetite",
      "count": 222
    },
    {
      "term": "Skin hyperaemia",
      "count": 219
    },
    {
      "term": "Shaking",
      "count": 218
    },
    {
      "term": "Fever",
      "count": 217
    },
    {
      "term": "Alopecia NOS",
      "count": 213
    },
    {
      "term": "Dermatitis",
      "count": 207
    },
    {
      "term": "Hyperglycaemia",
      "count": 204
    },
    {
      "term": "Pyoderma",
      "count": 200
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 199
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 197
    },
    {
      "term": "Seizure NOS",
      "count": 195
    },
    {
      "term": "Vocalisation",
      "count": 192
    },
    {
      "term": "Elevated total bilirubin",
      "count": 185
    },
    {
      "term": "Pale mucous membrane",
      "count": 182
    },
    {
      "term": "Hair shedding",
      "count": 178
    },
    {
      "term": "Urinary tract infection",
      "count": 174
    },
    {
      "term": "Lymphadenopathy",
      "count": 166
    },
    {
      "term": "Neutrophilia",
      "count": 163
    },
    {
      "term": "Proteinuria",
      "count": 161
    },
    {
      "term": "Weakness",
      "count": 161
    },
    {
      "term": "Decreased urine concentration",
      "count": 159
    },
    {
      "term": "Haematuria",
      "count": 156
    },
    {
      "term": "Elevated creatinine",
      "count": 155
    },
    {
      "term": "Abdominal pain",
      "count": 150
    },
    {
      "term": "Skin and/or appendage neoplasm NOS",
      "count": 149
    },
    {
      "term": "Nausea",
      "count": 148
    },
    {
      "term": "Pain NOS",
      "count": 148
    },
    {
      "term": "Not eating",
      "count": 146
    },
    {
      "term": "Otitis externa",
      "count": 139
    },
    {
      "term": "Urinary incontinence",
      "count": 136
    },
    {
      "term": "Aggression",
      "count": 134
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 134
    },
    {
      "term": "Elevated liver enzymes",
      "count": 133
    },
    {
      "term": "Neoplasia NOS",
      "count": 133
    },
    {
      "term": "Underdose",
      "count": 132
    },
    {
      "term": "Leucopenia NOS",
      "count": 131
    },
    {
      "term": "Cough",
      "count": 130
    },
    {
      "term": "Dehydration",
      "count": 130
    },
    {
      "term": "Inappetence",
      "count": 128
    },
    {
      "term": "Diabetes mellitus",
      "count": 127
    },
    {
      "term": "Thrombocytopenia",
      "count": 127
    },
    {
      "term": "Lameness",
      "count": 126
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 123
    },
    {
      "term": "PR-SKIN, LESION(S)",
      "count": 123
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 122
    },
    {
      "term": "Skin lump",
      "count": 119
    },
    {
      "term": "Elevated globulins",
      "count": 116
    },
    {
      "term": "Tachypnoea",
      "count": 115
    },
    {
      "term": "Anaphylaxis",
      "count": 113
    },
    {
      "term": "Dyspnoea",
      "count": 110
    },
    {
      "term": "Anxiety",
      "count": 108
    },
    {
      "term": "Crust",
      "count": 107
    },
    {
      "term": "Tachycardia",
      "count": 102
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 100
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 97
    },
    {
      "term": "Lymphoma",
      "count": 97
    },
    {
      "term": "Twitching",
      "count": 97
    },
    {
      "term": "Hypersalivation",
      "count": 96
    },
    {
      "term": "Allergic pruritus",
      "count": 95
    },
    {
      "term": "Apprehension",
      "count": 95
    },
    {
      "term": "Corneal ulcer",
      "count": 94
    },
    {
      "term": "Pancreatitis",
      "count": 94
    },
    {
      "term": "Urticaria",
      "count": 91
    },
    {
      "term": "Weight gain",
      "count": 91
    }
  ]
}