{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 199
    },
    {
      "term": "Anorexia",
      "count": 135
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 126
    },
    {
      "term": "Death by euthanasia",
      "count": 116
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 108
    },
    {
      "term": "Death",
      "count": 85
    },
    {
      "term": "Diarrhoea",
      "count": 79
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 76
    },
    {
      "term": "Leucocytosis NOS",
      "count": 71
    },
    {
      "term": "Emesis",
      "count": 65
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 65
    },
    {
      "term": "Weight loss",
      "count": 64
    },
    {
      "term": "Ataxia",
      "count": 63
    },
    {
      "term": "Not eating",
      "count": 63
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 62
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 62
    },
    {
      "term": "Anaemia NOS",
      "count": 61
    },
    {
      "term": "Seizure NOS",
      "count": 58
    },
    {
      "term": "Decreased appetite",
      "count": 55
    },
    {
      "term": "Elevated creatinine",
      "count": 52
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 52
    },
    {
      "term": "Neutrophilia",
      "count": 52
    },
    {
      "term": "Depression",
      "count": 49
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 48
    },
    {
      "term": "Elevated total bilirubin",
      "count": 46
    },
    {
      "term": "Fever",
      "count": 42
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 40
    },
    {
      "term": "Pain NOS",
      "count": 38
    },
    {
      "term": "Elevated liver enzymes",
      "count": 37
    },
    {
      "term": "Weakness",
      "count": 37
    },
    {
      "term": "Skin lesion NOS",
      "count": 35
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 34
    },
    {
      "term": "Polydipsia",
      "count": 34
    },
    {
      "term": "Thrombocytopenia",
      "count": 34
    },
    {
      "term": "Hyperphosphataemia",
      "count": 32
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 32
    },
    {
      "term": "Panting",
      "count": 30
    },
    {
      "term": "Polyuria",
      "count": 30
    },
    {
      "term": "Pale mucous membrane",
      "count": 28
    },
    {
      "term": "Abnormal cytology",
      "count": 26
    },
    {
      "term": "Cough",
      "count": 26
    },
    {
      "term": "Dehydration",
      "count": 26
    },
    {
      "term": "Bloody diarrhoea",
      "count": 25
    },
    {
      "term": "Elevated globulins",
      "count": 25
    },
    {
      "term": "Pruritus",
      "count": 25
    },
    {
      "term": "Urinary incontinence",
      "count": 24
    },
    {
      "term": "Icterus",
      "count": 23
    },
    {
      "term": "Vocalisation",
      "count": 23
    },
    {
      "term": "Decreased urine concentration",
      "count": 22
    },
    {
      "term": "Lymphopenia",
      "count": 22
    },
    {
      "term": "Proteinuria",
      "count": 22
    },
    {
      "term": "Walking difficulty",
      "count": 22
    },
    {
      "term": "Nasal discharge",
      "count": 21
    },
    {
      "term": "Shaking",
      "count": 21
    },
    {
      "term": "Hyperglycaemia",
      "count": 20
    },
    {
      "term": "Hypoglycaemia",
      "count": 20
    },
    {
      "term": "Hypoproteinaemia",
      "count": 20
    },
    {
      "term": "Lameness",
      "count": 20
    },
    {
      "term": "Not drinking",
      "count": 20
    },
    {
      "term": "Emesis (multiple)",
      "count": 19
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 19
    },
    {
      "term": "Hypersalivation",
      "count": 19
    },
    {
      "term": "Inappetence",
      "count": 19
    },
    {
      "term": "Bacterial skin infection NOS",
      "count": 18
    },
    {
      "term": "Blood in vomit",
      "count": 18
    },
    {
      "term": "Loose stool",
      "count": 18
    },
    {
      "term": "Monocytosis",
      "count": 18
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 18
    },
    {
      "term": "Renal failure",
      "count": 18
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 17
    },
    {
      "term": "Elevated lipase",
      "count": 17
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 17
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 17
    },
    {
      "term": "Abdominal pain",
      "count": 16
    },
    {
      "term": "Crust",
      "count": 16
    },
    {
      "term": "Elevated renal parameters",
      "count": 16
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 16
    },
    {
      "term": "Inappropriate urination",
      "count": 16
    },
    {
      "term": "Limb weakness",
      "count": 16
    },
    {
      "term": "Tachycardia",
      "count": 16
    },
    {
      "term": "Unable to stand",
      "count": 16
    },
    {
      "term": "Bruising",
      "count": 15
    },
    {
      "term": "Convulsion",
      "count": 15
    },
    {
      "term": "Elevated amylase",
      "count": 15
    },
    {
      "term": "Haematuria",
      "count": 15
    },
    {
      "term": "Head tilt - ear disorder",
      "count": 15
    },
    {
      "term": "Laboured breathing",
      "count": 15
    },
    {
      "term": "Leucopenia NOS",
      "count": 15
    },
    {
      "term": "Melaena",
      "count": 15
    },
    {
      "term": "Skin disorders NOS",
      "count": 15
    },
    {
      "term": "Tremor",
      "count": 15
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 15
    },
    {
      "term": "Adipsia",
      "count": 14
    },
    {
      "term": "Aggression",
      "count": 14
    },
    {
      "term": "Blindness",
      "count": 14
    },
    {
      "term": "Confusion",
      "count": 14
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 14
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 14
    },
    {
      "term": "Increased percentage reticulocytes",
      "count": 14
    },
    {
      "term": "Local swelling (not application site)",
      "count": 14
    }
  ]
}