{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 701
    },
    {
      "term": "Emesis",
      "count": 368
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 356
    },
    {
      "term": "Diarrhoea",
      "count": 214
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 207
    },
    {
      "term": "Overdose",
      "count": 190
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 182
    },
    {
      "term": "Anorexia",
      "count": 173
    },
    {
      "term": "Accidental exposure",
      "count": 166
    },
    {
      "term": "Death by euthanasia",
      "count": 137
    },
    {
      "term": "Seizure NOS",
      "count": 133
    },
    {
      "term": "Weight loss",
      "count": 120
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 118
    },
    {
      "term": "Death",
      "count": 117
    },
    {
      "term": "Decreased appetite",
      "count": 107
    },
    {
      "term": "Ataxia",
      "count": 99
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 99
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 97
    },
    {
      "term": "Not eating",
      "count": 96
    },
    {
      "term": "Pruritus",
      "count": 94
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 84
    },
    {
      "term": "Leucocytosis NOS",
      "count": 73
    },
    {
      "term": "Panting",
      "count": 68
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 67
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 64
    },
    {
      "term": "Skin lesion NOS",
      "count": 63
    },
    {
      "term": "Fever",
      "count": 62
    },
    {
      "term": "Elevated total bilirubin",
      "count": 61
    },
    {
      "term": "Elevated liver enzymes",
      "count": 59
    },
    {
      "term": "INEFFECTIVE, ATOPY CONTROL",
      "count": 59
    },
    {
      "term": "Polydipsia",
      "count": 58
    },
    {
      "term": "Anaemia NOS",
      "count": 55
    },
    {
      "term": "Skin disorders NOS",
      "count": 55
    },
    {
      "term": "Emesis (multiple)",
      "count": 54
    },
    {
      "term": "Neutrophilia",
      "count": 54
    },
    {
      "term": "Weakness",
      "count": 54
    },
    {
      "term": "Dehydration",
      "count": 51
    },
    {
      "term": "Elevated creatinine",
      "count": 51
    },
    {
      "term": "Cough",
      "count": 50
    },
    {
      "term": "Polyuria",
      "count": 50
    },
    {
      "term": "Thrombocytopenia",
      "count": 50
    },
    {
      "term": "Shaking",
      "count": 48
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 47
    },
    {
      "term": "Abnormal cytology",
      "count": 45
    },
    {
      "term": "Bacterial skin infection NOS",
      "count": 45
    },
    {
      "term": "Inappetence",
      "count": 45
    },
    {
      "term": "Walking difficulty",
      "count": 45
    },
    {
      "term": "Lack of efficacy (ectoparasite) - flea",
      "count": 42
    },
    {
      "term": "Pale mucous membrane",
      "count": 42
    },
    {
      "term": "Dermatitis",
      "count": 41
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 41
    },
    {
      "term": "Pyoderma",
      "count": 41
    },
    {
      "term": "Loose stool",
      "count": 40
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 37
    },
    {
      "term": "Underdose",
      "count": 37
    },
    {
      "term": "Aggression",
      "count": 36
    },
    {
      "term": "Drooling",
      "count": 36
    },
    {
      "term": "Pain NOS",
      "count": 36
    },
    {
      "term": "Hyperglycaemia",
      "count": 35
    },
    {
      "term": "Depression",
      "count": 34
    },
    {
      "term": "Hyperphosphataemia",
      "count": 34
    },
    {
      "term": "Tremor",
      "count": 34
    },
    {
      "term": "Crust",
      "count": 33
    },
    {
      "term": "Not drinking",
      "count": 33
    },
    {
      "term": "Vocalisation",
      "count": 33
    },
    {
      "term": "Trembling",
      "count": 32
    },
    {
      "term": "Decreased urine concentration",
      "count": 31
    },
    {
      "term": "Disorientation",
      "count": 31
    },
    {
      "term": "Neutropenia",
      "count": 31
    },
    {
      "term": "Urinary incontinence",
      "count": 31
    },
    {
      "term": "Bloody diarrhoea",
      "count": 30
    },
    {
      "term": "Lymphopenia",
      "count": 30
    },
    {
      "term": "Monocytosis",
      "count": 30
    },
    {
      "term": "Hypersalivation",
      "count": 29
    },
    {
      "term": "Proteinuria",
      "count": 29
    },
    {
      "term": "Urinary tract infection",
      "count": 29
    },
    {
      "term": "Intestinal perforation",
      "count": 28
    },
    {
      "term": "Itching",
      "count": 28
    },
    {
      "term": "Skin and tissue infection NOS",
      "count": 28
    },
    {
      "term": "Icterus",
      "count": 27
    },
    {
      "term": "Leucopenia NOS",
      "count": 27
    },
    {
      "term": "Lymphadenopathy",
      "count": 27
    },
    {
      "term": "Dermal mass",
      "count": 26
    },
    {
      "term": "Inappropriate urination",
      "count": 26
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 25
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 25
    },
    {
      "term": "Reddening of the skin",
      "count": 25
    },
    {
      "term": "Skin scab",
      "count": 25
    },
    {
      "term": "Twitching",
      "count": 25
    },
    {
      "term": "Elevated renal parameters",
      "count": 24
    },
    {
      "term": "Hypoproteinaemia",
      "count": 24
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 23
    },
    {
      "term": "Anxiety",
      "count": 22
    },
    {
      "term": "INEFFECTIVE, HEARTWORM LARVAE",
      "count": 22
    },
    {
      "term": "INEFFECTIVE, LOSS OF EFFECT",
      "count": 22
    },
    {
      "term": "Ocular discharge",
      "count": 22
    },
    {
      "term": "Restlessness",
      "count": 22
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 22
    },
    {
      "term": "Laboured breathing",
      "count": 21
    },
    {
      "term": "Lateral recumbency",
      "count": 21
    }
  ]
}