{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 703
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 444
    },
    {
      "term": "Anorexia",
      "count": 371
    },
    {
      "term": "Diarrhoea",
      "count": 314
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 307
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 257
    },
    {
      "term": "Emesis",
      "count": 252
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 248
    },
    {
      "term": "Death by euthanasia",
      "count": 228
    },
    {
      "term": "Seizure NOS",
      "count": 214
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 196
    },
    {
      "term": "Death",
      "count": 177
    },
    {
      "term": "Pruritus",
      "count": 173
    },
    {
      "term": "Polydipsia",
      "count": 168
    },
    {
      "term": "Depression",
      "count": 166
    },
    {
      "term": "Polyuria",
      "count": 159
    },
    {
      "term": "Ataxia",
      "count": 158
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 154
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 152
    },
    {
      "term": "Fever",
      "count": 146
    },
    {
      "term": "Weight loss",
      "count": 146
    },
    {
      "term": "Anaemia NOS",
      "count": 145
    },
    {
      "term": "Decreased appetite",
      "count": 137
    },
    {
      "term": "Leucocytosis NOS",
      "count": 135
    },
    {
      "term": "Not eating",
      "count": 120
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 119
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 118
    },
    {
      "term": "Elevated creatinine",
      "count": 118
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 116
    },
    {
      "term": "Skin lesion NOS",
      "count": 116
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 114
    },
    {
      "term": "Elevated total bilirubin",
      "count": 108
    },
    {
      "term": "Thrombocytopenia",
      "count": 104
    },
    {
      "term": "Bacterial skin infection NOS",
      "count": 96
    },
    {
      "term": "Elevated liver enzymes",
      "count": 93
    },
    {
      "term": "Abnormal cytology",
      "count": 90
    },
    {
      "term": "INEFFECTIVE, ATOPY CONTROL",
      "count": 90
    },
    {
      "term": "Pain NOS",
      "count": 88
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 85
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 83
    },
    {
      "term": "Inappetence",
      "count": 83
    },
    {
      "term": "Neutrophilia",
      "count": 83
    },
    {
      "term": "Vocalisation",
      "count": 83
    },
    {
      "term": "Crust",
      "count": 82
    },
    {
      "term": "Panting",
      "count": 82
    },
    {
      "term": "Urinary tract infection",
      "count": 82
    },
    {
      "term": "Dermatitis",
      "count": 78
    },
    {
      "term": "Pale mucous membrane",
      "count": 73
    },
    {
      "term": "Shaking",
      "count": 72
    },
    {
      "term": "Proteinuria",
      "count": 71
    },
    {
      "term": "Convulsion",
      "count": 69
    },
    {
      "term": "Weakness",
      "count": 69
    },
    {
      "term": "Restlessness",
      "count": 67
    },
    {
      "term": "Pyoderma",
      "count": 66
    },
    {
      "term": "Dehydration",
      "count": 64
    },
    {
      "term": "Hyperphosphataemia",
      "count": 64
    },
    {
      "term": "Loose stool",
      "count": 63
    },
    {
      "term": "Skin disorders NOS",
      "count": 62
    },
    {
      "term": "Emesis (multiple)",
      "count": 61
    },
    {
      "term": "Neutropenia",
      "count": 61
    },
    {
      "term": "Urinary incontinence",
      "count": 61
    },
    {
      "term": "Leucopenia NOS",
      "count": 59
    },
    {
      "term": "Trembling",
      "count": 58
    },
    {
      "term": "Decreased urine concentration",
      "count": 57
    },
    {
      "term": "Icterus",
      "count": 55
    },
    {
      "term": "Anxiety",
      "count": 54
    },
    {
      "term": "Bloody diarrhoea",
      "count": 54
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 53
    },
    {
      "term": "Skin scab",
      "count": 53
    },
    {
      "term": "PR-SKIN, LESION(S)",
      "count": 52
    },
    {
      "term": "Haematuria",
      "count": 51
    },
    {
      "term": "Inappropriate urination",
      "count": 51
    },
    {
      "term": "Reddening of the skin",
      "count": 51
    },
    {
      "term": "Tremor",
      "count": 51
    },
    {
      "term": "Underdose",
      "count": 51
    },
    {
      "term": "Lymphopenia",
      "count": 50
    },
    {
      "term": "INEFFECTIVE, ANTIBIOTIC",
      "count": 49
    },
    {
      "term": "Lameness",
      "count": 48
    },
    {
      "term": "INEFFECTIVE, LOSS OF EFFECT",
      "count": 47
    },
    {
      "term": "Skin and tissue infection NOS",
      "count": 47
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 46
    },
    {
      "term": "Hyperglycaemia",
      "count": 46
    },
    {
      "term": "Itching",
      "count": 44
    },
    {
      "term": "Skin ulcer",
      "count": 44
    },
    {
      "term": "Deafness",
      "count": 43
    },
    {
      "term": "Disorientation",
      "count": 43
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 43
    },
    {
      "term": "Hypersalivation",
      "count": 43
    },
    {
      "term": "Monocytosis",
      "count": 43
    },
    {
      "term": "Tachycardia",
      "count": 43
    },
    {
      "term": "Elevated amylase",
      "count": 42
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 42
    },
    {
      "term": "Low platelet count",
      "count": 42
    },
    {
      "term": "Otitis externa",
      "count": 40
    },
    {
      "term": "Reluctant to move",
      "count": 40
    },
    {
      "term": "Urticaria",
      "count": 40
    },
    {
      "term": "Aggression",
      "count": 39
    },
    {
      "term": "Cough",
      "count": 39
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 39
    },
    {
      "term": "Overdose",
      "count": 39
    }
  ]
}