{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 715
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 629
    },
    {
      "term": "Anorexia",
      "count": 490
    },
    {
      "term": "Death",
      "count": 412
    },
    {
      "term": "Diarrhoea",
      "count": 316
    },
    {
      "term": "Death by euthanasia",
      "count": 283
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 240
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 224
    },
    {
      "term": "Seizure NOS",
      "count": 207
    },
    {
      "term": "Anaemia NOS",
      "count": 205
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 205
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 200
    },
    {
      "term": "Not eating",
      "count": 199
    },
    {
      "term": "Fever",
      "count": 198
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 190
    },
    {
      "term": "Depression",
      "count": 187
    },
    {
      "term": "Leucocytosis NOS",
      "count": 174
    },
    {
      "term": "Decreased appetite",
      "count": 171
    },
    {
      "term": "Ataxia",
      "count": 170
    },
    {
      "term": "Weight loss",
      "count": 167
    },
    {
      "term": "Anaphylaxis",
      "count": 153
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 151
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 147
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 131
    },
    {
      "term": "Pruritus",
      "count": 131
    },
    {
      "term": "Skin lesion NOS",
      "count": 128
    },
    {
      "term": "Thrombocytopenia",
      "count": 121
    },
    {
      "term": "Pale mucous membrane",
      "count": 120
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 114
    },
    {
      "term": "Neutrophilia",
      "count": 109
    },
    {
      "term": "Pain NOS",
      "count": 106
    },
    {
      "term": "Vocalisation",
      "count": 103
    },
    {
      "term": "Dehydration",
      "count": 102
    },
    {
      "term": "Emesis",
      "count": 99
    },
    {
      "term": "Weakness",
      "count": 94
    },
    {
      "term": "Panting",
      "count": 92
    },
    {
      "term": "Elevated creatinine",
      "count": 91
    },
    {
      "term": "Polydipsia",
      "count": 91
    },
    {
      "term": "Elevated total bilirubin",
      "count": 90
    },
    {
      "term": "Injection site pain",
      "count": 90
    },
    {
      "term": "Inappetence",
      "count": 89
    },
    {
      "term": "Elevated liver enzymes",
      "count": 88
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 87
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 86
    },
    {
      "term": "Shaking",
      "count": 84
    },
    {
      "term": "Polyuria",
      "count": 83
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 80
    },
    {
      "term": "INEFFECTIVE, ANTIBIOTIC",
      "count": 77
    },
    {
      "term": "Hyperphosphataemia",
      "count": 75
    },
    {
      "term": "Cough",
      "count": 73
    },
    {
      "term": "Dyspnoea",
      "count": 73
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 71
    },
    {
      "term": "Bruising",
      "count": 70
    },
    {
      "term": "Adipsia",
      "count": 68
    },
    {
      "term": "Hives (see also 'Skin')",
      "count": 67
    },
    {
      "term": "Urticaria",
      "count": 67
    },
    {
      "term": "Bloody diarrhoea",
      "count": 65
    },
    {
      "term": "Hyperglycaemia",
      "count": 63
    },
    {
      "term": "Leucopenia NOS",
      "count": 63
    },
    {
      "term": "Hypothermia",
      "count": 62
    },
    {
      "term": "Hypersalivation",
      "count": 61
    },
    {
      "term": "Immune mediated haemolytic anaemia",
      "count": 61
    },
    {
      "term": "Injection site swelling",
      "count": 59
    },
    {
      "term": "Not drinking",
      "count": 59
    },
    {
      "term": "Loose stool",
      "count": 57
    },
    {
      "term": "Intentional misuse",
      "count": 55
    },
    {
      "term": "Crust",
      "count": 52
    },
    {
      "term": "Dermatitis",
      "count": 52
    },
    {
      "term": "Reluctant to move",
      "count": 52
    },
    {
      "term": "Restlessness",
      "count": 52
    },
    {
      "term": "Emesis (multiple)",
      "count": 51
    },
    {
      "term": "Convulsion",
      "count": 50
    },
    {
      "term": "INEFFECTIVE, ATOPY CONTROL",
      "count": 50
    },
    {
      "term": "Unable to stand",
      "count": 50
    },
    {
      "term": "Hypoglycaemia",
      "count": 49
    },
    {
      "term": "PR-SKIN, LESION(S)",
      "count": 49
    },
    {
      "term": "Proteinuria",
      "count": 49
    },
    {
      "term": "Walking difficulty",
      "count": 49
    },
    {
      "term": "Trembling",
      "count": 48
    },
    {
      "term": "Abdominal pain",
      "count": 47
    },
    {
      "term": "Neutropenia",
      "count": 47
    },
    {
      "term": "Urinary incontinence",
      "count": 47
    },
    {
      "term": "Breathing difficulty",
      "count": 46
    },
    {
      "term": "Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders')",
      "count": 46
    },
    {
      "term": "Facial oedema",
      "count": 46
    },
    {
      "term": "Lateral recumbency",
      "count": 46
    },
    {
      "term": "Monocytosis",
      "count": 46
    },
    {
      "term": "Urinary tract infection",
      "count": 45
    },
    {
      "term": "Nausea",
      "count": 44
    },
    {
      "term": "Disorientation",
      "count": 43
    },
    {
      "term": "Tachycardia",
      "count": 43
    },
    {
      "term": "Cyanosis",
      "count": 42
    },
    {
      "term": "Haematuria",
      "count": 42
    },
    {
      "term": "Hypoproteinaemia",
      "count": 42
    },
    {
      "term": "Skin scab",
      "count": 42
    },
    {
      "term": "Tremor",
      "count": 42
    },
    {
      "term": "Reddening of the skin",
      "count": 41
    },
    {
      "term": "Malaise",
      "count": 40
    },
    {
      "term": "Nasal discharge",
      "count": 40
    },
    {
      "term": "Neurological signs NOS",
      "count": 40
    }
  ]
}