{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 12429
    },
    {
      "term": "Anorexia",
      "count": 9595
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 8565
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 7598
    },
    {
      "term": "Depression",
      "count": 5983
    },
    {
      "term": "Diarrhoea",
      "count": 5141
    },
    {
      "term": "Elevated total bilirubin",
      "count": 4414
    },
    {
      "term": "Death by euthanasia",
      "count": 4316
    },
    {
      "term": "Death",
      "count": 4191
    },
    {
      "term": "Accidental exposure",
      "count": 4133
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 3392
    },
    {
      "term": "Elevated creatinine",
      "count": 2938
    },
    {
      "term": "Icterus",
      "count": 2698
    },
    {
      "term": "Anaemia NOS",
      "count": 2683
    },
    {
      "term": "Weight loss",
      "count": 2631
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 2592
    },
    {
      "term": "Leucocytosis NOS",
      "count": 2582
    },
    {
      "term": "Elevated liver enzymes",
      "count": 2461
    },
    {
      "term": "Ataxia",
      "count": 2372
    },
    {
      "term": "Polydipsia",
      "count": 2313
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 2074
    },
    {
      "term": "No sign",
      "count": 1987
    },
    {
      "term": "Thrombocytopenia",
      "count": 1769
    },
    {
      "term": "Polyuria",
      "count": 1670
    },
    {
      "term": "Bloody diarrhoea",
      "count": 1586
    },
    {
      "term": "Convulsion",
      "count": 1580
    },
    {
      "term": "Fever",
      "count": 1486
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 1482
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 1435
    },
    {
      "term": "Weakness",
      "count": 1416
    },
    {
      "term": "Melaena",
      "count": 1411
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 1402
    },
    {
      "term": "PR-LIVER, LESION(S)",
      "count": 1261
    },
    {
      "term": "Hyperphosphataemia",
      "count": 1225
    },
    {
      "term": "Haematuria",
      "count": 1190
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 1180
    },
    {
      "term": "Decreased appetite",
      "count": 1138
    },
    {
      "term": "Dehydration",
      "count": 1116
    },
    {
      "term": "Not eating",
      "count": 1098
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 1073
    },
    {
      "term": "Blood in vomit",
      "count": 1003
    },
    {
      "term": "Seizure NOS",
      "count": 974
    },
    {
      "term": "Neutrophilia",
      "count": 971
    },
    {
      "term": "Emesis",
      "count": 967
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 928
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 927
    },
    {
      "term": "Proteinuria",
      "count": 924
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 889
    },
    {
      "term": "Decreased urine concentration",
      "count": 884
    },
    {
      "term": "Urinary incontinence",
      "count": 873
    },
    {
      "term": "Polypnoea",
      "count": 855
    },
    {
      "term": "Labelled drug-drug interaction medication error",
      "count": 842
    },
    {
      "term": "Pale mucous membrane",
      "count": 821
    },
    {
      "term": "Pain NOS",
      "count": 785
    },
    {
      "term": "Hypoproteinaemia",
      "count": 773
    },
    {
      "term": "Abdominal pain",
      "count": 758
    },
    {
      "term": "Panting",
      "count": 724
    },
    {
      "term": "Vocalisation",
      "count": 719
    },
    {
      "term": "Restlessness",
      "count": 718
    },
    {
      "term": "Hind limb paresis",
      "count": 707
    },
    {
      "term": "Elevated amylase",
      "count": 702
    },
    {
      "term": "Dyspnoea",
      "count": 696
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 684
    },
    {
      "term": "Recumbency",
      "count": 665
    },
    {
      "term": "INEFFECTIVE, ANTIINFLAMMATORY",
      "count": 660
    },
    {
      "term": "Pruritus",
      "count": 653
    },
    {
      "term": "Confusion",
      "count": 637
    },
    {
      "term": "Renal failure",
      "count": 608
    },
    {
      "term": "ULTRASOUND, LIVER ABNORMAL",
      "count": 604
    },
    {
      "term": "Lameness",
      "count": 577
    },
    {
      "term": "Inappetence",
      "count": 575
    },
    {
      "term": "Injection site swelling",
      "count": 575
    },
    {
      "term": "Reluctant to move",
      "count": 570
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 563
    },
    {
      "term": "Bilirubinuria",
      "count": 555
    },
    {
      "term": "Hepatopathy",
      "count": 554
    },
    {
      "term": "Hyperglycaemia",
      "count": 553
    },
    {
      "term": "Adipsia",
      "count": 538
    },
    {
      "term": "Trembling",
      "count": 528
    },
    {
      "term": "Loose stool",
      "count": 520
    },
    {
      "term": "Hypersalivation",
      "count": 519
    },
    {
      "term": "Coagulopathy",
      "count": 509
    },
    {
      "term": "Tachycardia",
      "count": 495
    },
    {
      "term": "Elevated renal parameters",
      "count": 493
    },
    {
      "term": "Skin lesion NOS",
      "count": 491
    },
    {
      "term": "Shaking",
      "count": 479
    },
    {
      "term": "Leucopenia NOS",
      "count": 474
    },
    {
      "term": "Hypoglycaemia",
      "count": 467
    },
    {
      "term": "Monocytosis",
      "count": 464
    },
    {
      "term": "Elevated lipase",
      "count": 463
    },
    {
      "term": "Aggression",
      "count": 458
    },
    {
      "term": "Haematochezia",
      "count": 456
    },
    {
      "term": "Urinary tract infection",
      "count": 456
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 454
    },
    {
      "term": "Cough",
      "count": 451
    },
    {
      "term": "Overdose",
      "count": 443
    },
    {
      "term": "Epistaxis",
      "count": 442
    },
    {
      "term": "PR-KIDNEY(S), LESION(S)",
      "count": 429
    },
    {
      "term": "Immune mediated haemolytic anaemia",
      "count": 425
    },
    {
      "term": "Ascites",
      "count": 422
    }
  ]
}