{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 128
    },
    {
      "term": "Hypersalivation",
      "count": 124
    },
    {
      "term": "Bradycardia",
      "count": 115
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 106
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 90
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 86
    },
    {
      "term": "Death by euthanasia",
      "count": 82
    },
    {
      "term": "Not eating",
      "count": 79
    },
    {
      "term": "Hypotension",
      "count": 73
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 67
    },
    {
      "term": "Weight loss",
      "count": 54
    },
    {
      "term": "Hyperglycaemia",
      "count": 49
    },
    {
      "term": "Foaming at the mouth",
      "count": 48
    },
    {
      "term": "Drooling",
      "count": 46
    },
    {
      "term": "Hiding",
      "count": 46
    },
    {
      "term": "Death",
      "count": 43
    },
    {
      "term": "Decreased appetite",
      "count": 43
    },
    {
      "term": "Diarrhoea",
      "count": 38
    },
    {
      "term": "Dehydration",
      "count": 35
    },
    {
      "term": "Lateral recumbency",
      "count": 35
    },
    {
      "term": "Anorexia",
      "count": 31
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 29
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 29
    },
    {
      "term": "Ataxia",
      "count": 28
    },
    {
      "term": "Decreased heart rate",
      "count": 28
    },
    {
      "term": "Low blood pressure",
      "count": 28
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 27
    },
    {
      "term": "Anaemia NOS",
      "count": 26
    },
    {
      "term": "Third eyelid protrusion",
      "count": 26
    },
    {
      "term": "Vocalisation",
      "count": 25
    },
    {
      "term": "UNPALATABLE",
      "count": 24
    },
    {
      "term": "Unresponsive to stimuli",
      "count": 23
    },
    {
      "term": "Fever",
      "count": 22
    },
    {
      "term": "Weakness",
      "count": 22
    },
    {
      "term": "Decreased haematocrit",
      "count": 21
    },
    {
      "term": "Elevated total bilirubin",
      "count": 21
    },
    {
      "term": "Hypothermia",
      "count": 21
    },
    {
      "term": "Elevated creatinine",
      "count": 20
    },
    {
      "term": "Sedation",
      "count": 19
    },
    {
      "term": "Gagging",
      "count": 17
    },
    {
      "term": "Nausea",
      "count": 17
    },
    {
      "term": "Dull",
      "count": 16
    },
    {
      "term": "Malaise",
      "count": 16
    },
    {
      "term": "Neutrophilia",
      "count": 16
    },
    {
      "term": "Reluctant to move",
      "count": 16
    },
    {
      "term": "Overdose",
      "count": 15
    },
    {
      "term": "Pale mucous membrane",
      "count": 15
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 14
    },
    {
      "term": "Not drinking",
      "count": 14
    },
    {
      "term": "Diabetic ketoacidosis",
      "count": 13
    },
    {
      "term": "Emesis (multiple)",
      "count": 13
    },
    {
      "term": "Hypokalaemia",
      "count": 13
    },
    {
      "term": "Inappetence",
      "count": 13
    },
    {
      "term": "Leucocytosis NOS",
      "count": 13
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 12
    },
    {
      "term": "Breathing difficulty",
      "count": 12
    },
    {
      "term": "Decreased packed cell volume (PCV)",
      "count": 12
    },
    {
      "term": "Ketosis",
      "count": 12
    },
    {
      "term": "Nasal discharge",
      "count": 12
    },
    {
      "term": "Glucosuria",
      "count": 11
    },
    {
      "term": "Heart murmur",
      "count": 11
    },
    {
      "term": "Tachypnoea",
      "count": 11
    },
    {
      "term": "Unwell",
      "count": 11
    },
    {
      "term": "Anaphylaxis",
      "count": 10
    },
    {
      "term": "Constipation",
      "count": 10
    },
    {
      "term": "Decreased red blood cell count",
      "count": 10
    },
    {
      "term": "Depression",
      "count": 10
    },
    {
      "term": "Dilated pupils",
      "count": 10
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 10
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 10
    },
    {
      "term": "Falling",
      "count": 10
    },
    {
      "term": "Inappropriate urination",
      "count": 10
    },
    {
      "term": "Increased respiratory rate",
      "count": 10
    },
    {
      "term": "Monocytosis",
      "count": 10
    },
    {
      "term": "Not himself/herself",
      "count": 10
    },
    {
      "term": "Open mouth breathing",
      "count": 10
    },
    {
      "term": "Panting",
      "count": 10
    },
    {
      "term": "Renal disorder NOS",
      "count": 10
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 9
    },
    {
      "term": "Hyperphosphataemia",
      "count": 9
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 9
    },
    {
      "term": "Intentional misuse",
      "count": 9
    },
    {
      "term": "Laboured breathing",
      "count": 9
    },
    {
      "term": "Lymphocytosis",
      "count": 9
    },
    {
      "term": "Not urinating",
      "count": 9
    },
    {
      "term": "Pain NOS",
      "count": 9
    },
    {
      "term": "Recumbency",
      "count": 9
    },
    {
      "term": "Decreased respiratory rate",
      "count": 8
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 8
    },
    {
      "term": "High pancreatic-specific lipase",
      "count": 8
    },
    {
      "term": "Hypochloraemia",
      "count": 8
    },
    {
      "term": "Pleural effusion",
      "count": 8
    },
    {
      "term": "Proteinuria",
      "count": 8
    },
    {
      "term": "Retching",
      "count": 8
    },
    {
      "term": "Accidental exposure",
      "count": 7
    },
    {
      "term": "Blood in urine",
      "count": 7
    },
    {
      "term": "Collapse NOS (see also Cardio-vascular and Neurological disorders)",
      "count": 7
    },
    {
      "term": "Decreased body temperature",
      "count": 7
    },
    {
      "term": "Distress",
      "count": 7
    },
    {
      "term": "Dyspnoea",
      "count": 7
    }
  ]
}