{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 576
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 537
    },
    {
      "term": "Death",
      "count": 449
    },
    {
      "term": "Diarrhoea",
      "count": 368
    },
    {
      "term": "Bradycardia",
      "count": 350
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 324
    },
    {
      "term": "Anorexia",
      "count": 300
    },
    {
      "term": "Injection site swelling",
      "count": 267
    },
    {
      "term": "Death by euthanasia",
      "count": 242
    },
    {
      "term": "Seizure NOS",
      "count": 241
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 230
    },
    {
      "term": "Cardiac arrest",
      "count": 219
    },
    {
      "term": "Not eating",
      "count": 207
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 195
    },
    {
      "term": "Pain NOS",
      "count": 187
    },
    {
      "term": "Tachycardia",
      "count": 186
    },
    {
      "term": "Panting",
      "count": 180
    },
    {
      "term": "INEFFECTIVE, SEDATION",
      "count": 178
    },
    {
      "term": "Bloody diarrhoea",
      "count": 172
    },
    {
      "term": "Vocalisation",
      "count": 169
    },
    {
      "term": "Decreased appetite",
      "count": 167
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 166
    },
    {
      "term": "Fever",
      "count": 165
    },
    {
      "term": "Pale mucous membrane",
      "count": 142
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 134
    },
    {
      "term": "Sedation prolonged",
      "count": 132
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 119
    },
    {
      "term": "Underdose",
      "count": 119
    },
    {
      "term": "Ataxia",
      "count": 118
    },
    {
      "term": "Weight loss",
      "count": 118
    },
    {
      "term": "Leucocytosis NOS",
      "count": 116
    },
    {
      "term": "Apnoea",
      "count": 113
    },
    {
      "term": "Elevated total bilirubin",
      "count": 111
    },
    {
      "term": "Injection site pain",
      "count": 111
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 108
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 105
    },
    {
      "term": "Sedation",
      "count": 104
    },
    {
      "term": "Anaphylaxis",
      "count": 103
    },
    {
      "term": "Dehydration",
      "count": 101
    },
    {
      "term": "Neutrophilia",
      "count": 101
    },
    {
      "term": "Wound",
      "count": 100
    },
    {
      "term": "Recovery prolonged",
      "count": 99
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 95
    },
    {
      "term": "Hypersalivation",
      "count": 93
    },
    {
      "term": "Depression",
      "count": 91
    },
    {
      "term": "Anaemia NOS",
      "count": 90
    },
    {
      "term": "Cyanosis",
      "count": 89
    },
    {
      "term": "Elevated creatinine",
      "count": 89
    },
    {
      "term": "Respiratory arrest",
      "count": 85
    },
    {
      "term": "Swelling NOS",
      "count": 85
    },
    {
      "term": "Swollen limb",
      "count": 80
    },
    {
      "term": "Hypothermia",
      "count": 77
    },
    {
      "term": "Intentional misuse",
      "count": 77
    },
    {
      "term": "INEFFECTIVE, REVERSAL",
      "count": 76
    },
    {
      "term": "Lameness",
      "count": 75
    },
    {
      "term": "Drooling",
      "count": 74
    },
    {
      "term": "Hypotension",
      "count": 74
    },
    {
      "term": "Emesis (multiple)",
      "count": 73
    },
    {
      "term": "Anxiety",
      "count": 72
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 72
    },
    {
      "term": "Shaking",
      "count": 71
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 70
    },
    {
      "term": "Hyperglycaemia",
      "count": 70
    },
    {
      "term": "Weakness",
      "count": 68
    },
    {
      "term": "Drug administration error",
      "count": 67
    },
    {
      "term": "Emesis",
      "count": 67
    },
    {
      "term": "Licking at injection site",
      "count": 67
    },
    {
      "term": "Elevated liver enzymes",
      "count": 66
    },
    {
      "term": "Injection site bleeding",
      "count": 66
    },
    {
      "term": "Thrombocytopenia",
      "count": 66
    },
    {
      "term": "Dyspnoea",
      "count": 65
    },
    {
      "term": "Injection site skin discolouration",
      "count": 65
    },
    {
      "term": "Restlessness",
      "count": 65
    },
    {
      "term": "Bruising",
      "count": 64
    },
    {
      "term": "Twitching",
      "count": 64
    },
    {
      "term": "Polydipsia",
      "count": 63
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 62
    },
    {
      "term": "Injection site necrosis",
      "count": 62
    },
    {
      "term": "Tachypnoea",
      "count": 62
    },
    {
      "term": "Cough",
      "count": 61
    },
    {
      "term": "Lack of efficacy (neoplasia, partial remission)",
      "count": 61
    },
    {
      "term": "Regurgitation",
      "count": 61
    },
    {
      "term": "Convulsion",
      "count": 60
    },
    {
      "term": "Limb non-weight bearing",
      "count": 60
    },
    {
      "term": "Monocytosis",
      "count": 60
    },
    {
      "term": "Reluctant to move",
      "count": 60
    },
    {
      "term": "Local swelling (not application site)",
      "count": 59
    },
    {
      "term": "Injection site scab",
      "count": 58
    },
    {
      "term": "Blood in vomit",
      "count": 56
    },
    {
      "term": "Hyperphosphataemia",
      "count": 56
    },
    {
      "term": "Injection site lump",
      "count": 56
    },
    {
      "term": "Polyuria",
      "count": 56
    },
    {
      "term": "Inappetence",
      "count": 55
    },
    {
      "term": "Injection site complication NOS",
      "count": 55
    },
    {
      "term": "Overdose",
      "count": 54
    },
    {
      "term": "Hyperthermia",
      "count": 53
    },
    {
      "term": "Icterus",
      "count": 53
    },
    {
      "term": "Lateral recumbency",
      "count": 53
    },
    {
      "term": "Injection site bruising",
      "count": 52
    },
    {
      "term": "Trembling",
      "count": 52
    }
  ]
}