{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 287
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 220
    },
    {
      "term": "Diarrhoea",
      "count": 191
    },
    {
      "term": "Death by euthanasia",
      "count": 186
    },
    {
      "term": "Anorexia",
      "count": 169
    },
    {
      "term": "Death",
      "count": 168
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 146
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 131
    },
    {
      "term": "Not eating",
      "count": 127
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 126
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 121
    },
    {
      "term": "Pain NOS",
      "count": 115
    },
    {
      "term": "Panting",
      "count": 111
    },
    {
      "term": "Vocalisation",
      "count": 111
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 108
    },
    {
      "term": "Leucocytosis NOS",
      "count": 106
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 101
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 101
    },
    {
      "term": "Fever",
      "count": 98
    },
    {
      "term": "Decreased appetite",
      "count": 97
    },
    {
      "term": "Neutrophilia",
      "count": 92
    },
    {
      "term": "Dehydration",
      "count": 89
    },
    {
      "term": "Seizure NOS",
      "count": 89
    },
    {
      "term": "Injection site swelling",
      "count": 88
    },
    {
      "term": "Elevated total bilirubin",
      "count": 87
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 81
    },
    {
      "term": "Tachycardia",
      "count": 77
    },
    {
      "term": "Hypersalivation",
      "count": 74
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 74
    },
    {
      "term": "Bradycardia",
      "count": 71
    },
    {
      "term": "Anaemia NOS",
      "count": 68
    },
    {
      "term": "Weight loss",
      "count": 68
    },
    {
      "term": "Bloody diarrhoea",
      "count": 67
    },
    {
      "term": "Elevated creatinine",
      "count": 64
    },
    {
      "term": "Pale mucous membrane",
      "count": 63
    },
    {
      "term": "Cardiac arrest",
      "count": 62
    },
    {
      "term": "Emesis",
      "count": 62
    },
    {
      "term": "Hypothermia",
      "count": 60
    },
    {
      "term": "Thrombocytopenia",
      "count": 60
    },
    {
      "term": "Monocytosis",
      "count": 58
    },
    {
      "term": "Abdominal pain",
      "count": 57
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 55
    },
    {
      "term": "Elevated liver enzymes",
      "count": 54
    },
    {
      "term": "Hyperphosphataemia",
      "count": 54
    },
    {
      "term": "Injection site pain",
      "count": 54
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 52
    },
    {
      "term": "Hyperglycaemia",
      "count": 50
    },
    {
      "term": "Hypoproteinaemia",
      "count": 49
    },
    {
      "term": "Lymphopenia",
      "count": 48
    },
    {
      "term": "Inappetence",
      "count": 47
    },
    {
      "term": "Neutropenia",
      "count": 46
    },
    {
      "term": "Weakness",
      "count": 46
    },
    {
      "term": "Ataxia",
      "count": 45
    },
    {
      "term": "Drooling",
      "count": 42
    },
    {
      "term": "Bruising",
      "count": 41
    },
    {
      "term": "Icterus",
      "count": 40
    },
    {
      "term": "Regurgitation",
      "count": 40
    },
    {
      "term": "Dry mucous membrane",
      "count": 39
    },
    {
      "term": "Lateral recumbency",
      "count": 39
    },
    {
      "term": "Depression",
      "count": 38
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 37
    },
    {
      "term": "Hypokalaemia",
      "count": 37
    },
    {
      "term": "Hyponatremia",
      "count": 37
    },
    {
      "term": "Hypotension",
      "count": 37
    },
    {
      "term": "Loose stool",
      "count": 37
    },
    {
      "term": "Not drinking",
      "count": 37
    },
    {
      "term": "Pancreatitis",
      "count": 37
    },
    {
      "term": "Anaphylaxis",
      "count": 36
    },
    {
      "term": "Hypoglycaemia",
      "count": 36
    },
    {
      "term": "Nausea",
      "count": 36
    },
    {
      "term": "Hypochloraemia",
      "count": 35
    },
    {
      "term": "Leucopenia NOS",
      "count": 35
    },
    {
      "term": "Shaking",
      "count": 35
    },
    {
      "term": "Tachypnoea",
      "count": 35
    },
    {
      "term": "Uncomfortable",
      "count": 35
    },
    {
      "term": "Abnormal cytology",
      "count": 34
    },
    {
      "term": "Cough",
      "count": 33
    },
    {
      "term": "Tense abdomen",
      "count": 33
    },
    {
      "term": "Reluctant to move",
      "count": 32
    },
    {
      "term": "Underdose",
      "count": 32
    },
    {
      "term": "Injection site necrosis",
      "count": 31
    },
    {
      "term": "Overdose",
      "count": 31
    },
    {
      "term": "Local swelling (not application site)",
      "count": 30
    },
    {
      "term": "Blood in vomit",
      "count": 29
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 29
    },
    {
      "term": "Eosinopenia",
      "count": 29
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 29
    },
    {
      "term": "Inappropriate urination",
      "count": 29
    },
    {
      "term": "Low platelet count",
      "count": 29
    },
    {
      "term": "Walking difficulty",
      "count": 29
    },
    {
      "term": "Abnormal breathing",
      "count": 28
    },
    {
      "term": "Elevated amylase",
      "count": 28
    },
    {
      "term": "Sedation",
      "count": 28
    },
    {
      "term": "Skin lesion NOS",
      "count": 28
    },
    {
      "term": "Dyspnoea",
      "count": 27
    },
    {
      "term": "Increased respiratory rate",
      "count": 27
    },
    {
      "term": "Lack of efficacy (endoparasite) - heartworm",
      "count": 27
    },
    {
      "term": "Gall bladder & bile duct disorder NOS",
      "count": 26
    },
    {
      "term": "Intestinal perforation",
      "count": 26
    },
    {
      "term": "Restlessness",
      "count": 26
    }
  ]
}