{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 1418
    },
    {
      "term": "Anorexia",
      "count": 801
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 720
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 597
    },
    {
      "term": "Diarrhoea",
      "count": 569
    },
    {
      "term": "Death by euthanasia",
      "count": 538
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 532
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 528
    },
    {
      "term": "Death",
      "count": 522
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 510
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 478
    },
    {
      "term": "Leucocytosis NOS",
      "count": 438
    },
    {
      "term": "Anaemia NOS",
      "count": 382
    },
    {
      "term": "Fever",
      "count": 378
    },
    {
      "term": "Depression",
      "count": 369
    },
    {
      "term": "Decreased appetite",
      "count": 338
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 335
    },
    {
      "term": "Weight loss",
      "count": 332
    },
    {
      "term": "Ataxia",
      "count": 307
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 307
    },
    {
      "term": "Emesis",
      "count": 304
    },
    {
      "term": "Elevated total bilirubin",
      "count": 303
    },
    {
      "term": "Not eating",
      "count": 295
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 284
    },
    {
      "term": "Neutrophilia",
      "count": 275
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 263
    },
    {
      "term": "Urinary tract infection",
      "count": 261
    },
    {
      "term": "Polydipsia",
      "count": 259
    },
    {
      "term": "Seizure NOS",
      "count": 256
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 225
    },
    {
      "term": "Polyuria",
      "count": 222
    },
    {
      "term": "Elevated creatinine",
      "count": 206
    },
    {
      "term": "Thrombocytopenia",
      "count": 203
    },
    {
      "term": "Dehydration",
      "count": 198
    },
    {
      "term": "Elevated liver enzymes",
      "count": 197
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 191
    },
    {
      "term": "Cough",
      "count": 179
    },
    {
      "term": "Pruritus",
      "count": 174
    },
    {
      "term": "Proteinuria",
      "count": 169
    },
    {
      "term": "Haematuria",
      "count": 168
    },
    {
      "term": "Hyperphosphataemia",
      "count": 168
    },
    {
      "term": "Icterus",
      "count": 164
    },
    {
      "term": "Weakness",
      "count": 164
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 163
    },
    {
      "term": "Panting",
      "count": 163
    },
    {
      "term": "Pale mucous membrane",
      "count": 156
    },
    {
      "term": "Pain NOS",
      "count": 150
    },
    {
      "term": "Urinary incontinence",
      "count": 149
    },
    {
      "term": "Skin lesion NOS",
      "count": 148
    },
    {
      "term": "Vocalisation",
      "count": 148
    },
    {
      "term": "Hyperglycaemia",
      "count": 138
    },
    {
      "term": "Inappetence",
      "count": 135
    },
    {
      "term": "Elevated gamma-glutamyl transferase (GGT)",
      "count": 130
    },
    {
      "term": "Monocytosis",
      "count": 128
    },
    {
      "term": "Shaking",
      "count": 125
    },
    {
      "term": "Convulsion",
      "count": 119
    },
    {
      "term": "Dyspnoea",
      "count": 117
    },
    {
      "term": "No sign",
      "count": 116
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 114
    },
    {
      "term": "Lymphopenia",
      "count": 108
    },
    {
      "term": "Abdominal pain",
      "count": 106
    },
    {
      "term": "Hypoproteinaemia",
      "count": 101
    },
    {
      "term": "Lameness",
      "count": 100
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 100
    },
    {
      "term": "Bloody diarrhoea",
      "count": 99
    },
    {
      "term": "Inappropriate urination",
      "count": 99
    },
    {
      "term": "Leucopenia NOS",
      "count": 98
    },
    {
      "term": "Overdose",
      "count": 97
    },
    {
      "term": "Trembling",
      "count": 97
    },
    {
      "term": "Ocular discharge",
      "count": 95
    },
    {
      "term": "Tachycardia",
      "count": 94
    },
    {
      "term": "Emesis (multiple)",
      "count": 93
    },
    {
      "term": "Pneumonia",
      "count": 93
    },
    {
      "term": "Hypersalivation",
      "count": 92
    },
    {
      "term": "Nasal discharge",
      "count": 92
    },
    {
      "term": "Abnormal cytology",
      "count": 90
    },
    {
      "term": "Loose stool",
      "count": 90
    },
    {
      "term": "Blood in urine",
      "count": 89
    },
    {
      "term": "Reluctant to move",
      "count": 88
    },
    {
      "term": "Elevated cholesterol (total)",
      "count": 87
    },
    {
      "term": "Decreased urine concentration",
      "count": 86
    },
    {
      "term": "Elevated amylase",
      "count": 84
    },
    {
      "term": "Intentional misuse",
      "count": 84
    },
    {
      "term": "Restlessness",
      "count": 82
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 79
    },
    {
      "term": "Adipsia",
      "count": 77
    },
    {
      "term": "Hypoglycaemia",
      "count": 77
    },
    {
      "term": "Underdose",
      "count": 77
    },
    {
      "term": "Melaena",
      "count": 76
    },
    {
      "term": "Tachypnoea",
      "count": 76
    },
    {
      "term": "Dermatitis",
      "count": 75
    },
    {
      "term": "Hyperkalaemia",
      "count": 75
    },
    {
      "term": "Immune mediated haemolytic anaemia",
      "count": 75
    },
    {
      "term": "Walking difficulty",
      "count": 75
    },
    {
      "term": "Elevated globulins",
      "count": 74
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 72
    },
    {
      "term": "Injection site swelling",
      "count": 72
    },
    {
      "term": "Low platelet count",
      "count": 72
    },
    {
      "term": "Facial swelling (see also 'Skin')",
      "count": 71
    },
    {
      "term": "Not drinking",
      "count": 70
    }
  ]
}