{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 756
    },
    {
      "term": "Anorexia",
      "count": 435
    },
    {
      "term": "Diarrhoea",
      "count": 370
    },
    {
      "term": "Lack of efficacy (bacteria) - NOS",
      "count": 272
    },
    {
      "term": "Death",
      "count": 267
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 240
    },
    {
      "term": "Death by euthanasia",
      "count": 226
    },
    {
      "term": "Depression",
      "count": 206
    },
    {
      "term": "Weight loss",
      "count": 177
    },
    {
      "term": "Ataxia",
      "count": 160
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 153
    },
    {
      "term": "Fever",
      "count": 147
    },
    {
      "term": "Dehydration",
      "count": 125
    },
    {
      "term": "Not eating",
      "count": 124
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 115
    },
    {
      "term": "Anaemia NOS",
      "count": 113
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 112
    },
    {
      "term": "Hyperglycaemia",
      "count": 107
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 102
    },
    {
      "term": "Hypersalivation",
      "count": 101
    },
    {
      "term": "Decreased appetite",
      "count": 86
    },
    {
      "term": "Vocalisation",
      "count": 85
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 83
    },
    {
      "term": "Hypothermia",
      "count": 83
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 82
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 80
    },
    {
      "term": "Elevated creatinine",
      "count": 79
    },
    {
      "term": "Hiding",
      "count": 71
    },
    {
      "term": "Leucocytosis NOS",
      "count": 70
    },
    {
      "term": "Weakness",
      "count": 68
    },
    {
      "term": "Pruritus",
      "count": 63
    },
    {
      "term": "Convulsion",
      "count": 62
    },
    {
      "term": "Emesis",
      "count": 60
    },
    {
      "term": "No sign",
      "count": 59
    },
    {
      "term": "Seizure NOS",
      "count": 59
    },
    {
      "term": "Elevated total bilirubin",
      "count": 58
    },
    {
      "term": "Sneezing",
      "count": 58
    },
    {
      "term": "Dyspnoea",
      "count": 57
    },
    {
      "term": "Inappetence",
      "count": 53
    },
    {
      "term": "Hyperphosphataemia",
      "count": 52
    },
    {
      "term": "Urinary tract infection",
      "count": 49
    },
    {
      "term": "Neutrophilia",
      "count": 48
    },
    {
      "term": "Pale mucous membrane",
      "count": 48
    },
    {
      "term": "Adipsia",
      "count": 47
    },
    {
      "term": "Ketosis",
      "count": 47
    },
    {
      "term": "Color, Abnormal",
      "count": 46
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 44
    },
    {
      "term": "Polydipsia",
      "count": 44
    },
    {
      "term": "Skin lesion NOS",
      "count": 44
    },
    {
      "term": "Haematuria",
      "count": 43
    },
    {
      "term": "Overdose",
      "count": 43
    },
    {
      "term": "Accidental exposure",
      "count": 40
    },
    {
      "term": "Pain NOS",
      "count": 40
    },
    {
      "term": "Thrombocytopenia",
      "count": 40
    },
    {
      "term": "Nasal discharge",
      "count": 38
    },
    {
      "term": "Not drinking",
      "count": 38
    },
    {
      "term": "Blindness",
      "count": 37
    },
    {
      "term": "Inappropriate urination",
      "count": 37
    },
    {
      "term": "Constipation",
      "count": 36
    },
    {
      "term": "Drooling",
      "count": 36
    },
    {
      "term": "Loose stool",
      "count": 36
    },
    {
      "term": "Mydriasis",
      "count": 36
    },
    {
      "term": "Anaphylaxis",
      "count": 35
    },
    {
      "term": "Dilated pupils",
      "count": 35
    },
    {
      "term": "Polyuria",
      "count": 35
    },
    {
      "term": "Twitching",
      "count": 35
    },
    {
      "term": "Alopecia NOS",
      "count": 33
    },
    {
      "term": "Intentional misuse",
      "count": 33
    },
    {
      "term": "Tachypnoea",
      "count": 33
    },
    {
      "term": "Anisocoria",
      "count": 32
    },
    {
      "term": "Proteinuria",
      "count": 32
    },
    {
      "term": "Underdose",
      "count": 32
    },
    {
      "term": "Blood in urine",
      "count": 31
    },
    {
      "term": "Hypoglycaemia",
      "count": 31
    },
    {
      "term": "Recumbency",
      "count": 31
    },
    {
      "term": "Application site alopecia",
      "count": 30
    },
    {
      "term": "Icterus",
      "count": 30
    },
    {
      "term": "Leucopenia NOS",
      "count": 29
    },
    {
      "term": "Digestive tract disorder NOS",
      "count": 28
    },
    {
      "term": "Elevated serum alkaline phosphatase (SAP)",
      "count": 28
    },
    {
      "term": "Emesis (multiple)",
      "count": 28
    },
    {
      "term": "Foaming at the mouth",
      "count": 28
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 28
    },
    {
      "term": "Ocular discharge",
      "count": 28
    },
    {
      "term": "Urine abnormalities NOS",
      "count": 28
    },
    {
      "term": "Skin scab",
      "count": 27
    },
    {
      "term": "Trembling",
      "count": 27
    },
    {
      "term": "Disorientation",
      "count": 26
    },
    {
      "term": "Elevated globulins",
      "count": 26
    },
    {
      "term": "INEFFECTIVE, ANTIBIOTIC",
      "count": 26
    },
    {
      "term": "Cough",
      "count": 25
    },
    {
      "term": "Crust",
      "count": 25
    },
    {
      "term": "Elevated liver enzymes",
      "count": 25
    },
    {
      "term": "Glucosuria",
      "count": 25
    },
    {
      "term": "Heart murmur",
      "count": 25
    },
    {
      "term": "Reluctant to move",
      "count": 25
    },
    {
      "term": "Hyperactivity",
      "count": 24
    },
    {
      "term": "Open mouth breathing",
      "count": 24
    },
    {
      "term": "Tachycardia",
      "count": 24
    },
    {
      "term": "Collapse (see also 'Cardio-vascular' and 'Systemic disorders')",
      "count": 23
    }
  ]
}