{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Death",
      "count": 65
    },
    {
      "term": "Tachycardia",
      "count": 42
    },
    {
      "term": "Cardiac arrest",
      "count": 41
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 40
    },
    {
      "term": "Vomiting",
      "count": 39
    },
    {
      "term": "Seizure NOS",
      "count": 38
    },
    {
      "term": "Vocalisation",
      "count": 37
    },
    {
      "term": "Bradycardia",
      "count": 36
    },
    {
      "term": "Paddling",
      "count": 35
    },
    {
      "term": "Diarrhoea",
      "count": 34
    },
    {
      "term": "Apnoea",
      "count": 29
    },
    {
      "term": "Cyanosis",
      "count": 25
    },
    {
      "term": "Twitching",
      "count": 22
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 21
    },
    {
      "term": "Excitation",
      "count": 21
    },
    {
      "term": "Hypotension",
      "count": 21
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 21
    },
    {
      "term": "Intentional misuse",
      "count": 20
    },
    {
      "term": "Not eating",
      "count": 20
    },
    {
      "term": "Nystagmus",
      "count": 20
    },
    {
      "term": "Injection site swelling",
      "count": 17
    },
    {
      "term": "Decreased appetite",
      "count": 14
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 14
    },
    {
      "term": "Ataxia",
      "count": 13
    },
    {
      "term": "Death by euthanasia",
      "count": 13
    },
    {
      "term": "Injection site scab",
      "count": 13
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 13
    },
    {
      "term": "Rough recovery",
      "count": 13
    },
    {
      "term": "Bloody diarrhoea",
      "count": 12
    },
    {
      "term": "Dysphoria",
      "count": 12
    },
    {
      "term": "Muscle tremor",
      "count": 12
    },
    {
      "term": "Emesis (multiple)",
      "count": 11
    },
    {
      "term": "Hypoalbuminaemia",
      "count": 11
    },
    {
      "term": "Pale mucous membrane",
      "count": 11
    },
    {
      "term": "Recovery prolonged",
      "count": 11
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 10
    },
    {
      "term": "Aggression",
      "count": 10
    },
    {
      "term": "Anaphylaxis",
      "count": 10
    },
    {
      "term": "Cardiorespiratory arrest",
      "count": 10
    },
    {
      "term": "Convulsion",
      "count": 10
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 10
    },
    {
      "term": "Horizontal nystagmus",
      "count": 10
    },
    {
      "term": "Medication error NOS",
      "count": 10
    },
    {
      "term": "Monocytosis",
      "count": 10
    },
    {
      "term": "Neutrophilia",
      "count": 10
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 10
    },
    {
      "term": "Regurgitation",
      "count": 10
    },
    {
      "term": "Respiratory arrest",
      "count": 10
    },
    {
      "term": "Hyperthermia",
      "count": 9
    },
    {
      "term": "Injection site thickening",
      "count": 9
    },
    {
      "term": "Local swelling (not application site)",
      "count": 9
    },
    {
      "term": "Pruritus",
      "count": 9
    },
    {
      "term": "Arrhythmia",
      "count": 8
    },
    {
      "term": "Fever",
      "count": 8
    },
    {
      "term": "Grand mal seizure",
      "count": 8
    },
    {
      "term": "Hypothermia",
      "count": 8
    },
    {
      "term": "Panting",
      "count": 8
    },
    {
      "term": "Tachypnoea",
      "count": 8
    },
    {
      "term": "Underdose",
      "count": 8
    },
    {
      "term": "Abnormal cytology",
      "count": 7
    },
    {
      "term": "Anxiety",
      "count": 7
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 7
    },
    {
      "term": "Duodenal ulcer",
      "count": 7
    },
    {
      "term": "Hypertension",
      "count": 7
    },
    {
      "term": "Injection site complication NOS",
      "count": 7
    },
    {
      "term": "Injection site lesion",
      "count": 7
    },
    {
      "term": "Injection site pain",
      "count": 7
    },
    {
      "term": "Leucocytosis NOS",
      "count": 7
    },
    {
      "term": "Pain NOS",
      "count": 7
    },
    {
      "term": "Tonic-clonic seizure",
      "count": 7
    },
    {
      "term": "Uncomfortable",
      "count": 7
    },
    {
      "term": "Agitation",
      "count": 6
    },
    {
      "term": "Anorexia",
      "count": 6
    },
    {
      "term": "Blood in vomit",
      "count": 6
    },
    {
      "term": "Distension of abdomen",
      "count": 6
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 6
    },
    {
      "term": "Elevated creatinine",
      "count": 6
    },
    {
      "term": "Erythema (for urticaria see Immune SOC)",
      "count": 6
    },
    {
      "term": "Extensor rigidity",
      "count": 6
    },
    {
      "term": "Facial swelling (see also Skin)",
      "count": 6
    },
    {
      "term": "Hypersalivation",
      "count": 6
    },
    {
      "term": "Hypokalaemia",
      "count": 6
    },
    {
      "term": "Inappetence",
      "count": 6
    },
    {
      "term": "Malodour",
      "count": 6
    },
    {
      "term": "Nausea",
      "count": 6
    },
    {
      "term": "Peritonitis",
      "count": 6
    },
    {
      "term": "Polydipsia",
      "count": 6
    },
    {
      "term": "Polyuria",
      "count": 6
    },
    {
      "term": "Premature ventricular contractions",
      "count": 6
    },
    {
      "term": "Reluctant to move",
      "count": 6
    },
    {
      "term": "Shaking",
      "count": 6
    },
    {
      "term": "Tremor",
      "count": 6
    },
    {
      "term": "Weakness",
      "count": 6
    },
    {
      "term": "Cough",
      "count": 5
    },
    {
      "term": "Depression",
      "count": 5
    },
    {
      "term": "Dyspnoea",
      "count": 5
    },
    {
      "term": "Elevated aspartate aminotransferase (AST)",
      "count": 5
    },
    {
      "term": "Elevated creatine-kinase (CK)",
      "count": 5
    },
    {
      "term": "Elevated lactate",
      "count": 5
    },
    {
      "term": "Elevated total bilirubin",
      "count": 5
    }
  ]
}