{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Not eating",
      "count": 53
    },
    {
      "term": "Death",
      "count": 52
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 36
    },
    {
      "term": "Bradycardia",
      "count": 32
    },
    {
      "term": "Anorexia",
      "count": 29
    },
    {
      "term": "Dilated pupils",
      "count": 28
    },
    {
      "term": "Hypotension",
      "count": 27
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 27
    },
    {
      "term": "Recovery prolonged",
      "count": 27
    },
    {
      "term": "Death by euthanasia",
      "count": 26
    },
    {
      "term": "Hiding",
      "count": 26
    },
    {
      "term": "Hyperactivity",
      "count": 26
    },
    {
      "term": "Hypothermia",
      "count": 25
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 25
    },
    {
      "term": "Dehydration",
      "count": 24
    },
    {
      "term": "Vomiting",
      "count": 23
    },
    {
      "term": "Decreased appetite",
      "count": 22
    },
    {
      "term": "Cardiac arrest",
      "count": 21
    },
    {
      "term": "Cyanosis",
      "count": 21
    },
    {
      "term": "Twitching",
      "count": 21
    },
    {
      "term": "Ataxia",
      "count": 20
    },
    {
      "term": "Hyperthermia",
      "count": 20
    },
    {
      "term": "Diarrhoea",
      "count": 19
    },
    {
      "term": "Dysphoria",
      "count": 18
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 18
    },
    {
      "term": "Fever",
      "count": 17
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 16
    },
    {
      "term": "Elevated creatinine",
      "count": 16
    },
    {
      "term": "Not drinking",
      "count": 16
    },
    {
      "term": "Hyperphosphataemia",
      "count": 15
    },
    {
      "term": "Lethargy (see also Central nervous system depression in 'Neurological')",
      "count": 15
    },
    {
      "term": "Not sleeping",
      "count": 15
    },
    {
      "term": "Agitation",
      "count": 14
    },
    {
      "term": "Seizure NOS",
      "count": 14
    },
    {
      "term": "Application site alopecia",
      "count": 13
    },
    {
      "term": "Application site hair loss",
      "count": 13
    },
    {
      "term": "Hypokalaemia",
      "count": 13
    },
    {
      "term": "Intentional misuse",
      "count": 13
    },
    {
      "term": "Sedation",
      "count": 13
    },
    {
      "term": "Excitation",
      "count": 11
    },
    {
      "term": "Mydriasis",
      "count": 11
    },
    {
      "term": "Pale mucous membrane",
      "count": 11
    },
    {
      "term": "Anaemia NOS",
      "count": 10
    },
    {
      "term": "Apnoea",
      "count": 10
    },
    {
      "term": "Constipation",
      "count": 10
    },
    {
      "term": "Hyperglycaemia",
      "count": 10
    },
    {
      "term": "Not urinating",
      "count": 10
    },
    {
      "term": "Tremor",
      "count": 10
    },
    {
      "term": "Vocalisation",
      "count": 10
    },
    {
      "term": "Weight loss",
      "count": 10
    },
    {
      "term": "Anisocoria",
      "count": 9
    },
    {
      "term": "Elevated symmetrical dimethylarginine (SDMA)",
      "count": 9
    },
    {
      "term": "Hypersalivation",
      "count": 9
    },
    {
      "term": "Hyponatremia",
      "count": 9
    },
    {
      "term": "Limping",
      "count": 9
    },
    {
      "term": "Proteinuria",
      "count": 9
    },
    {
      "term": "Tachypnoea",
      "count": 9
    },
    {
      "term": "Cardiorespiratory arrest",
      "count": 8
    },
    {
      "term": "Extensor rigidity",
      "count": 8
    },
    {
      "term": "Heart murmur",
      "count": 8
    },
    {
      "term": "Hyperaesthesia",
      "count": 8
    },
    {
      "term": "Inappetence",
      "count": 8
    },
    {
      "term": "Neutrophilia",
      "count": 8
    },
    {
      "term": "Pacing",
      "count": 8
    },
    {
      "term": "Respiratory arrest",
      "count": 8
    },
    {
      "term": "Staring",
      "count": 8
    },
    {
      "term": "Urinary retention",
      "count": 8
    },
    {
      "term": "Adipsia",
      "count": 7
    },
    {
      "term": "Azotaemia",
      "count": 7
    },
    {
      "term": "Decreased haematocrit",
      "count": 7
    },
    {
      "term": "Disorientation",
      "count": 7
    },
    {
      "term": "Hypocalcaemia",
      "count": 7
    },
    {
      "term": "Inappropriate urination",
      "count": 7
    },
    {
      "term": "Muscle tremor",
      "count": 7
    },
    {
      "term": "Not himself/herself",
      "count": 7
    },
    {
      "term": "Opisthotonus",
      "count": 7
    },
    {
      "term": "Prolonged anaesthesia",
      "count": 7
    },
    {
      "term": "Tachycardia",
      "count": 7
    },
    {
      "term": "Aggression",
      "count": 6
    },
    {
      "term": "Anuria",
      "count": 6
    },
    {
      "term": "Application site reddening",
      "count": 6
    },
    {
      "term": "Cardiac disorder NOS",
      "count": 6
    },
    {
      "term": "Drooling",
      "count": 6
    },
    {
      "term": "Dull",
      "count": 6
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 6
    },
    {
      "term": "Foaming at the mouth",
      "count": 6
    },
    {
      "term": "Hypoglycaemia",
      "count": 6
    },
    {
      "term": "Hypophosphataemia",
      "count": 6
    },
    {
      "term": "Muscle rigidity",
      "count": 6
    },
    {
      "term": "Neutropenia",
      "count": 6
    },
    {
      "term": "Paddling",
      "count": 6
    },
    {
      "term": "Panting",
      "count": 6
    },
    {
      "term": "Renal disorder NOS",
      "count": 6
    },
    {
      "term": "Renal failure",
      "count": 6
    },
    {
      "term": "Shaking",
      "count": 6
    },
    {
      "term": "Unresponsive to stimuli",
      "count": 6
    },
    {
      "term": "Abnormal breathing",
      "count": 5
    },
    {
      "term": "Abnormal posture NOS",
      "count": 5
    },
    {
      "term": "Abnormal pupil light reflex",
      "count": 5
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 5
    }
  ]
}