{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-07-02"
  },
  "results": [
    {
      "term": "Vomiting",
      "count": 6980
    },
    {
      "term": "Lack of efficacy (endoparasite) - heartworm",
      "count": 5660
    },
    {
      "term": "Lethargy (see also Central nervous system depression in Neurological)",
      "count": 4447
    },
    {
      "term": "Lack of efficacy (endoparasite) - hookworm",
      "count": 4410
    },
    {
      "term": "Lack of efficacy (ectoparasite) - flea",
      "count": 4226
    },
    {
      "term": "Diarrhoea",
      "count": 3728
    },
    {
      "term": "Lack of efficacy (bacteria) - Borrelia",
      "count": 2919
    },
    {
      "term": "Seizure NOS",
      "count": 2799
    },
    {
      "term": "Medication error NOS",
      "count": 2774
    },
    {
      "term": "Lack of efficacy - NOS",
      "count": 2442
    },
    {
      "term": "Intentional misuse",
      "count": 2012
    },
    {
      "term": "Lack of efficacy (endoparasite) - roundworm NOS",
      "count": 1922
    },
    {
      "term": "Not eating",
      "count": 1769
    },
    {
      "term": "Death by euthanasia",
      "count": 1759
    },
    {
      "term": "Lack of efficacy (bacteria) - Anaplasma",
      "count": 1692
    },
    {
      "term": "Lack of efficacy (ectoparasite) - tick NOS",
      "count": 1621
    },
    {
      "term": "Emesis (multiple)",
      "count": 1612
    },
    {
      "term": "Death",
      "count": 1411
    },
    {
      "term": "Overdose",
      "count": 1279
    },
    {
      "term": "Ataxia",
      "count": 1265
    },
    {
      "term": "Lack of efficacy (endoparasite) - tapeworm",
      "count": 1171
    },
    {
      "term": "Elevated serum alkaline phosphatase (ALP)",
      "count": 1146
    },
    {
      "term": "Decreased appetite",
      "count": 1131
    },
    {
      "term": "Panting",
      "count": 1043
    },
    {
      "term": "Elevated alanine aminotransferase (ALT)",
      "count": 1042
    },
    {
      "term": "Behavioural disorder NOS",
      "count": 988
    },
    {
      "term": "Other abnormal test result NOS",
      "count": 950
    },
    {
      "term": "Weight loss",
      "count": 901
    },
    {
      "term": "Anorexia",
      "count": 849
    },
    {
      "term": "Shaking",
      "count": 821
    },
    {
      "term": "Polydipsia",
      "count": 809
    },
    {
      "term": "Lack of efficacy (bacteria) - Ehrlichia",
      "count": 781
    },
    {
      "term": "Polyuria",
      "count": 745
    },
    {
      "term": "Underdose",
      "count": 734
    },
    {
      "term": "Urinary incontinence",
      "count": 695
    },
    {
      "term": "Not himself/herself",
      "count": 674
    },
    {
      "term": "Abnormal radiograph finding",
      "count": 634
    },
    {
      "term": "Facial swelling (see also Skin)",
      "count": 629
    },
    {
      "term": "Weakness",
      "count": 617
    },
    {
      "term": "Bloody diarrhoea",
      "count": 616
    },
    {
      "term": "Pain NOS",
      "count": 608
    },
    {
      "term": "Itching",
      "count": 607
    },
    {
      "term": "Lack of efficacy (endoparasite) - whipworm",
      "count": 593
    },
    {
      "term": "Hives (see also Skin)",
      "count": 587
    },
    {
      "term": "Unable to walk",
      "count": 571
    },
    {
      "term": "Tremor",
      "count": 569
    },
    {
      "term": "Fever",
      "count": 563
    },
    {
      "term": "Limb weakness",
      "count": 561
    },
    {
      "term": "Falling",
      "count": 498
    },
    {
      "term": "Drooling",
      "count": 496
    },
    {
      "term": "Urinary tract infection",
      "count": 495
    },
    {
      "term": "Musculoskeletal disorder NOS",
      "count": 480
    },
    {
      "term": "Neutrophilia",
      "count": 467
    },
    {
      "term": "Anaemia NOS",
      "count": 459
    },
    {
      "term": "Inappropriate urination",
      "count": 454
    },
    {
      "term": "Vocalisation",
      "count": 448
    },
    {
      "term": "Elevated blood urea nitrogen (BUN)",
      "count": 443
    },
    {
      "term": "Leucocytosis NOS",
      "count": 439
    },
    {
      "term": "Partial lack of efficacy",
      "count": 432
    },
    {
      "term": "Administration error NOS",
      "count": 430
    },
    {
      "term": "Anaphylaxis",
      "count": 422
    },
    {
      "term": "Anxiety",
      "count": 411
    },
    {
      "term": "Unable to stand",
      "count": 404
    },
    {
      "term": "Proprioception deficit",
      "count": 402
    },
    {
      "term": "Not drinking",
      "count": 392
    },
    {
      "term": "Dehydration",
      "count": 388
    },
    {
      "term": "Disorientation",
      "count": 385
    },
    {
      "term": "Pale mucous membrane",
      "count": 381
    },
    {
      "term": "Cough",
      "count": 380
    },
    {
      "term": "Proteinuria",
      "count": 378
    },
    {
      "term": "Inappetence",
      "count": 369
    },
    {
      "term": "Wobbliness",
      "count": 363
    },
    {
      "term": "Walking difficulty",
      "count": 362
    },
    {
      "term": "Lameness",
      "count": 358
    },
    {
      "term": "Hypersensitivity reaction",
      "count": 355
    },
    {
      "term": "Injection site swelling",
      "count": 351
    },
    {
      "term": "Restlessness",
      "count": 336
    },
    {
      "term": "Lymphopenia",
      "count": 327
    },
    {
      "term": "Elevated liver enzymes NOS",
      "count": 325
    },
    {
      "term": "Reluctant to move",
      "count": 324
    },
    {
      "term": "Leucopenia NOS",
      "count": 323
    },
    {
      "term": "Loose stool",
      "count": 322
    },
    {
      "term": "Deafness",
      "count": 321
    },
    {
      "term": "Monocytosis",
      "count": 317
    },
    {
      "term": "Neutropenia",
      "count": 312
    },
    {
      "term": "Elevated creatinine",
      "count": 311
    },
    {
      "term": "Pruritus",
      "count": 310
    },
    {
      "term": "Decreased haematocrit",
      "count": 307
    },
    {
      "term": "Abnormal ultrasound finding",
      "count": 304
    },
    {
      "term": "Nausea",
      "count": 302
    },
    {
      "term": "Head tilt - neurological disorder (see also Head tilt - ear disorder)",
      "count": 301
    },
    {
      "term": "Scratching",
      "count": 299
    },
    {
      "term": "Soft stool",
      "count": 295
    },
    {
      "term": "Accidental exposure",
      "count": 292
    },
    {
      "term": "Low platelet count",
      "count": 292
    },
    {
      "term": "Hind limb paresis",
      "count": 286
    },
    {
      "term": "Elevated total bilirubin",
      "count": 285
    },
    {
      "term": "Collapse NOS (see also Cardio-vascular and Neurological disorders)",
      "count": 284
    },
    {
      "term": "Hyperglycaemia",
      "count": 280
    },
    {
      "term": "Tachycardia",
      "count": 276
    }
  ]
}